Evidence map›Paper›PMID 31540245›Full record

Observational studyNutrients2019

Urinary Taurine Excretion and Risk of Late Graft Failure in Renal Transplant Recipients.

Adrian Post, M Yusof Said, Antonio W Gomes-Neto, Jennifer van der Krogt, Pim de Blaauw, Stefan P Berger, Johanna M Geleijnse, Karin Borgonjen, Else van den Berg, Harry van Goor and 5 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Adrian PostDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands. a.post01@umcg.nl.ORCID 0000-0001-8645-1627
M Yusof SaidDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands. m.y.said@umcg.nl.
Antonio W Gomes-NetoDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands. a.w.gomes.neto@umcg.nl.
Jennifer van der KrogtDepartment of Laboratory Medicine, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands. j.van.der.krogt@umcg.nl.
Pim de BlaauwDepartment of Laboratory Medicine, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands. p.de.blaauw@umcg.nl.
Stefan P BergerDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands. s.p.berger@umcg.nl.
Johanna M GeleijnseDepartment of Human Nutrition and Health, Wageningen University, 6708 PB Wageningen, The Netherlands. marianne.geleijnse@wur.nl.ORCID 0000-0001-7638-0589
Karin BorgonjenDepartment of Human Nutrition and Health, Wageningen University, 6708 PB Wageningen, The Netherlands. karin.borgonjen@wur.nl.ORCID 0000-0003-0960-4487
Else van den BergDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands. e.van.den.berg@umcg.nl.
Harry van GoorDepartment of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands. h.van.goor@umcg.nl.ORCID 0000-0002-6670-1577
Gerald RimbachInstitute of Human Nutrition and Food Science, Christian-Albrechts-University of Kiel, 24118 Kiel, Germany. rimbach@foodsci.uni-kiel.de.
Ido P KemaDepartment of Laboratory Medicine, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands. i.p.kema@umcg.nl.
Dimitrios TsikasInstitute of Toxicology, Core Unit Proteomics, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany. tsikas.dimitros@mh-hannover.de.ORCID 0000-0001-6320-0956
M Rebecca Heiner-FokkemaDepartment of Laboratory Medicine, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands. m.r.heiner@umcg.nl.
Stephan J L BakkerDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands. s.j.l.bakker@umcg.nl.ORCID 0000-0003-3356-6791
University Medical Center Groningen · NLWageningen University & Research · NLChristian-Albrechts-Universität zu Kiel · DEMedizinische Hochschule Hannover · DE

Funding

Top Institute Food and Nutrition A-1003
6 · The paper itself

Abstract

Taurine is a sulfur containing nutrient that has been shown to protect against oxidative stress, which has been implicated in the pathophysiology leading to late graft failure after renal transplantation. We prospectively investigated whether high urinary taurine excretion, reflecting high taurine intake, is associated with low risk for development of late graft failure in renal transplant recipients (RTR). Urinary taurine excretion was measured in a longitudinal cohort of 678 stable RTR. Prospective associations were assessed using Cox regression analyses. Graft failure was defined as the start of dialysis or re-transplantation. In RTR (58% male, 53 ± 13 years old, estimated glomerular filtration rate (eGFR) 45 ± 19 mL/min/1.73 m

Indexed as

AdultAgedFemaleGraft RejectionGraft SurvivalHumansKidney TransplantationMaleMiddle AgedProportional Hazards ModelsProspective StudiesRisk FactorsTaurineTransplant RecipientsTaurinegraft survivalrenal transplant recipientstaurinetaurine excretion

Identifiers

PMID31540245
PMCPMC6770760
OpenAlexW2972637840

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.