Evidence map›Paper›PMID 31540125›Full record

ArticleInternational journal of molecular sciences2019

Invariant Natural Killer T-Cells and Total CD1d Restricted Cells Differentially Influence Lipid Metabolism and Atherosclerosis in Low Density Receptor Deficient Mice.

Paul A VanderLaan, Catherine A Reardon, Veneracion G Cabana, Chyung-Ru Wang, Godfrey S Getz

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. CIITA/PRMT5 promote CD4BMC medicine · 2026
    Article
  2. Review
  3. Insights from Murine Studies on the Site Specificity of Atherosclerosis.International journal of molecular sciences · 2024
    Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Paul A VanderLaanDepartment of Pathology, The University of Chicago, Chicago, IL 60637, USA. pvanderl@bidmc.harvard.edu.ORCID 0000-0002-7234-5652
Catherine A ReardonDepartment of Pathology, The University of Chicago, Chicago, IL 60637, USA. reardon@uchicago.edu.
Veneracion G CabanaDepartment of Pathology, The University of Chicago, Chicago, IL 60637, USA. vencabana@gmail.com.
Chyung-Ru WangDepartment of Microbiology and Immunology, Northwestern University, 633 Clark St, Evanston, IL 60208, USA. chyung-ru-wang@northwestern.edu.
Godfrey S GetzDepartment of Pathology, The University of Chicago, Chicago, IL 60637, USA. getz@bsd.uchicago.edu.
University of Chicago · USNorthwestern University · US

Funding

The Role of Group 1 CD1-restricted T Cells in Infectious DiseaseR01AI057460 · NIAID · UNIVERSITY OF CHICAGO · PI WANG, CHYUNG-RU · 2004 to 2020
$5.7M
The Regulation and Function of Murine CD1 MoleculesR01AI043407 · NIAID · UNIVERSITY OF CHICAGO · PI WANG, CHYUNG-RU · 1998 to 2017
$5.2M
NKT cells in lipoprotein Metabolism and atherosclerosisR01HL088420 · NHLBI · UNIVERSITY OF CHICAGO · PI GETZ, GODFREY SHALOM · 2008 to 2011
$1.5M
NHLBI NIH HHS HL088420NIAID NIH HHS R01 AI043407NIAID NIH HHS R01 AI057460
6 · The paper itself

Abstract

Natural killer T (NKT) cells are a distinct subset of lymphocytes that bridge the innate and adaptive immune response and can be divided into type I invariant NKT cells (iNKT) and type II NKT cells. The objective of this study is to examine the effects of NKT cell on lipid metabolism and the initiation and progression of atherosclerosis in LDL receptor deficient (LDLR

Indexed as

Adaptive ImmunityAnimalsAntigens, CD1dAortaAtherosclerosisCholesterolFemaleLipid MetabolismLipoproteinsMaleMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicNatural Killer T-CellsReceptors, LDLAntigens, CD1dCD1D protein, humanCholesterolLipoproteinsReceptors, LDLatherosclerosischolesterollipoproteinsNKT cells

Identifiers

PMID31540125
PMCPMC6770011
OpenAlexW2973215898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.