ArticleMicroorganisms2019
Nitric Oxide Donor Modulates a Multispecies Oral Bacterial Community-An In Vitro Study.
Article in Microorganisms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 17 citations in OpenAlex.
- Impact of a Specific Collagen Peptide Food Supplement on Periodontal Inflammation in Aftercare Patients-A Randomised Controlled Trial.Nutrients · 2022Trial
- The effects of nitrate on the oral microbiome: a systematic review investigating prebiotic potential.Journal of oral microbiology · 2024Review
- Microbial contamination of spittoons and germicidal effect of irradiation with krypton chloride excimer lamps (Far UV-C 222 nm).PloS one · 2024Article
- Interdental Plaque Microbial Community Changes under In Vitro Violet LED Irradiation.Antibiotics (Basel, Switzerland) · 2021Article
- Analyses of energy metabolism and stress defence provide insights intoGut pathogens · 2020Article
- Inter-site and interpersonal diversity of salivary and tongue microbiomes, and the effect of oral care tablets.F1000Research · 2020Article
- The Impact of Dental Environment Stress on Dentition Status, Salivary Nitric Oxide and Flow Rate.Journal of International Society of Preventive & Community DentistryArticle
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
The deterioration of human oral microbiota is known to not only cause oral diseases but also to affect systemic health. Various environmental factors are thought to influence the disruption and restoration of the oral ecosystem. In this study, we focused on the effect of nitric oxide (NO) produced by denitrification and NO synthase enzymes on dental plaque microbiota. Interdental plaques collected from 10 subjects were exposed to NO donor sodium nitroprusside (SNP) and then cultured in a specialized growth medium. Depending on the concentration of exposed SNP, a decrease in α-diversity and a continuous change in β-diversity in the dental plaque community were shown by sequencing bacterial 16S rRNA genes. We also identified eight operational taxonomic units that were significantly altered by NO exposure. Among them, the exposure of NO donors to
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.