Evidence map›Paper›PMID 31540019›Full record

ArticleInternational journal of molecular sciences2019

Myelin Disturbances Produced by Sub-Toxic Concentration of Heavy Metals: The Role of Oligodendrocyte Dysfunction.

Jessica Maiuolo, Roberta Macrì, Irene Bava, Micaela Gliozzi, Vincenzo Musolino, Saverio Nucera, Cristina Carresi, Miriam Scicchitano, Francesca Bosco, Federica Scarano and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
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  5. An Innovative Method of Improving an Extract ofInternational journal of molecular sciences · 2025
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  11. Protective Role of an Extract Waste Product fromPlants (Basel, Switzerland) · 2023
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  15. Review
  16. The Effect ofInternational journal of molecular sciences · 2021
    Article
  17. Article
  18. Combined Exposure to Metals in Drinking Water Alters the Dopamine System in Mouse Striatum.International journal of environmental research and public health · 2021
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Jessica MaiuoloInstitute of Research of Food Safety & Health (IRC-FSH), Department of Health Sciences, University "Magna Graecia", 88100 Catanzaro, Italy. jessicamaiuolo@virgilio.it.
Roberta MacrìInstitute of Research of Food Safety & Health (IRC-FSH), Department of Health Sciences, University "Magna Graecia", 88100 Catanzaro, Italy. robertamacri85@gmail.com.
Irene BavaInstitute of Research of Food Safety & Health (IRC-FSH), Department of Health Sciences, University "Magna Graecia", 88100 Catanzaro, Italy. irenebava@libero.it.
Micaela GliozziInstitute of Research of Food Safety & Health (IRC-FSH), Department of Health Sciences, University "Magna Graecia", 88100 Catanzaro, Italy. micaela.gliozzi@gmail.com.
Vincenzo MusolinoInstitute of Research of Food Safety & Health (IRC-FSH), Department of Health Sciences, University "Magna Graecia", 88100 Catanzaro, Italy. xabaras3@hotmail.com.
Saverio NuceraInstitute of Research of Food Safety & Health (IRC-FSH), Department of Health Sciences, University "Magna Graecia", 88100 Catanzaro, Italy. saverio.nucera@hotmail.it.
Cristina CarresiInstitute of Research of Food Safety & Health (IRC-FSH), Department of Health Sciences, University "Magna Graecia", 88100 Catanzaro, Italy. carresi@unicz.it.
Miriam ScicchitanoInstitute of Research of Food Safety & Health (IRC-FSH), Department of Health Sciences, University "Magna Graecia", 88100 Catanzaro, Italy. miriam.scicchitano@hotmail.it.
Francesca BoscoInstitute of Research of Food Safety & Health (IRC-FSH), Department of Health Sciences, University "Magna Graecia", 88100 Catanzaro, Italy. francescabosco@libero.it.
Federica ScaranoInstitute of Research of Food Safety & Health (IRC-FSH), Department of Health Sciences, University "Magna Graecia", 88100 Catanzaro, Italy. federicascar87@gmail.com.
Ernesto PalmaInstitute of Research of Food Safety & Health (IRC-FSH), Department of Health Sciences, University "Magna Graecia", 88100 Catanzaro, Italy. palma@unicz.it.ORCID 0000-0003-4199-207X
Santo GratteriInstitute of Research of Food Safety & Health (IRC-FSH), Department of Health Sciences, University "Magna Graecia", 88100 Catanzaro, Italy. gratteri@unicz.it.
Vincenzo MollaceInstitute of Research of Food Safety & Health (IRC-FSH), Department of Health Sciences, University "Magna Graecia", 88100 Catanzaro, Italy. mollace@libero.it.
Magna Graecia University · IT

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca PON03PE_00078_1 and PON03PE_00078_2
6 · The paper itself

Abstract

Evidence has been accumulated demonstrating that heavy metals may accumulate in various organs, leading to tissue damage and toxic effects in mammals. In particular, the Central Nervous System (CNS) seems to be particularly vulnerable to cumulative concentrations of heavy metals, though the pathophysiological mechanisms is still to be clarified. In particular, the potential role of oligodendrocyte dysfunction and myelin production after exposure to subtoxic concentration I confirmed. It is ok of heavy metals is to be better assessed. Here we investigated on the effect of sub-toxic concentration of several essential (Cu

Indexed as

CalciumCell DifferentiationCell LineCell SurvivalCentral Nervous SystemHumansMetals, HeavyMyelin Basic ProteinMyelin SheathNeurogenesisNeuronsOligodendrogliaCalciumMetals, HeavyMyelin Basic Proteinheavy metalsintracellular calcium regulationlipid formationmyelinationoligodendrocytes

Identifiers

PMID31540019
PMCPMC6769910
OpenAlexW2972675372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.