Evidence map›Paper›PMID 31540008›Full record

ArticleToxins2019

Twenty-Eight Fungal Secondary Metabolites Detected in Pig Feed Samples: Their Occurrence, Relevance and Cytotoxic Effects In Vitro.

Barbara Novak, Valentina Rainer, Michael Sulyok, Dietmar Haltrich, Gerd Schatzmayr, Elisabeth Mayer

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
8.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. An ABC-B Transporter Helps ProtectJournal of fungi (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Entomotoxic Activity of the Extracts from the Fungus,Journal of fungi (Basel, Switzerland) · 2021
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Toxins · 2020
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Barbara NovakBIOMIN Research Center, Technopark 1, 3430 Tulln, Austria. barbara.novak@biomin.net.
Valentina RainerBIOMIN Research Center, Technopark 1, 3430 Tulln, Austria. valentina.rainer@biomin.net.
Michael SulyokInstitute of Bioanalytics and Agro-Metabolomics, University of Natural Resources and Life Sciences, Konrad-Lorenz-Straße 20, 3430 Tulln, Austria. michael.sulyok@boku.ac.at.ORCID 0000-0002-3302-0732
Dietmar HaltrichFood Biotechnology Laboratory, Department of Food Science and Technology, University of Natural Resources and Life Sciences, Muthgasse 11, 1190 Vienna, Austria. dietmar.haltrich@boku.ac.at.ORCID 0000-0002-8722-8176
Gerd SchatzmayrBIOMIN Research Center, Technopark 1, 3430 Tulln, Austria. gerd.schatzmayr@biomin.net.ORCID 0000-0002-4325-855X
Elisabeth MayerBIOMIN Research Center, Technopark 1, 3430 Tulln, Austria. e.mayer@biomin.net.
BOKU University · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Feed samples are frequently contaminated by a wide range of chemically diverse natural products, which can be determined using highly sensitive analytical techniques. Next to already well-investigated mycotoxins, unknown or unregulated fungal secondary metabolites have also been found, some of which at significant concentrations. In our study, 1141 pig feed samples were analyzed for more than 800 secondary fungal metabolites using the same LC-MS/MS method and ranked according to their prevalence. Effects on the viability of the 28 most relevant were tested on an intestinal porcine epithelial cell line (IPEC-J2). The most frequently occurring compounds were determined as being cyclo-(L-Pro-L-Tyr), moniliformin, and enniatin B, followed by enniatin B1, aurofusarin, culmorin, and enniatin A1. The main mycotoxins, deoxynivalenol and zearalenone, were found only at ranks 8 and 10. Regarding cytotoxicity, apicidin, gliotoxin, bikaverin, and beauvericin led to lower IC

Indexed as

Animal FeedAnimalsCell LineCell SurvivalFood ContaminationFungiMycotoxinsSecondary MetabolismSwineMycotoxinsAlternariaAspergillusemerging mycotoxinfungiFusariumin vitroIPEC-J2occurrence dataPenicillium

Identifiers

PMID31540008
PMCPMC6784148
OpenAlexW2972992218

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.