Evidence map›Paper›PMID 31539931›Full record

ArticleOrganic letters2019

Characterization by Empirical and Computational Methods of Dictyospiromide, an Intriguing Antioxidant Alkaloid from the Marine Alga

Pengcheng Yan, Ge Li, Chaojie Wang, Jianzhang Wu, Zhongmin Sun, Gary E Martin, Xiao Wang, Mikhail Reibarkh, Josep Saurí, Kirk R Gustafson

Abstract read
In one paragraph

Article in Organic letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. The Biodiversity of the GenusMolecules (Basel, Switzerland) · 2022
    Review
  4. Metabolites with Antioxidant Activity from Marine Macroalgae.Antioxidants (Basel, Switzerland) · 2021
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Pengcheng YanSchool of Pharmaceutical Sciences , Wenzhou Medical University , Wenzhou , Zhejiang 325035 , People's Republic of China.ORCID 0000-0002-9114-2244
Ge LiSchool of Pharmaceutical Sciences , Wenzhou Medical University , Wenzhou , Zhejiang 325035 , People's Republic of China.
Chaojie WangSchool of Pharmaceutical Sciences , Wenzhou Medical University , Wenzhou , Zhejiang 325035 , People's Republic of China.
Jianzhang WuSchool of Pharmaceutical Sciences , Wenzhou Medical University , Wenzhou , Zhejiang 325035 , People's Republic of China.
Zhongmin SunInstitute of Oceanology , Chinese Academy of Sciences , Qingdao 266071 , People's Republic of China.
Gary E MartinDepartment of Chemistry and Biochemistry , Seton Hall University , South Orange , New Jersey 07079 , United States.
Xiao WangStructure Elucidation Group, Analytical Research and Development , Merck & Co. , Rahway , New Jersey 07065 , United States.ORCID 0000-0003-3238-5366
Mikhail ReibarkhStructure Elucidation Group, Analytical Research and Development , Merck & Co. , Rahway , New Jersey 07065 , United States.
Josep SauríStructure Elucidation Group, Analytical Research and Development , Merck & Co. , Boston , Massachusetts 02115 , United States.
Kirk R GustafsonMolecular Targets Program, Center for Cancer Research , National Cancer Institute , Frederick , Maryland 21702 , United States.ORCID 0000-0001-6821-4943

Funding

Natural Products Discovery and Characterization Through Network CollaborationsZIABC011568 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI DU, LIN · 2014 to 2025
$17.2M
Intramural NIH HHS ZIA BC011568
6 · The paper itself

Abstract

The challenging structural motif of dictyospiromide (

Indexed as

Density Functional TheoryAlkaloidsAnimalsAntioxidantsCell SurvivalMagnetic Resonance SpectroscopyMolecular ConformationNF-E2-Related Factor 2PC12 CellsPhaeophyceaeRatsSignal TransductionSpiro CompoundsSuccinimidesAlkaloidsAntioxidantsNfe2l2 protein, ratNF-E2-Related Factor 2Spiro CompoundssuccinimideSuccinimides

Identifiers

PMID31539931
PMCPMC7487124

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.