Evidence map›Paper›PMID 31538809›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2019

Thoracic spinal cord neuromodulation obtunds dorsal root ganglion afferent neuronal transduction of the ischemic ventricle.

Siamak Salavatian, Sarah M Ardell, Mathew Hammer, David Gibbons, J Andrew Armour, Jeffrey L Ardell

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Cardiac Neuroanatomy and Fundamentals of Neurocardiology.Cardiac electrophysiology clinics · 2024
    Review
  6. Real-time in vivo thoracic spinal glutamate sensing during myocardial ischemia.American journal of physiology. Heart and circulatory physiology · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Autonomic modulation of ventricular electrical activity: recent developments and clinical implications.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2021
    Review
  15. Article
  16. Article
  17. Hemodynamic assessment of diastolic function for experimental models.American journal of physiology. Heart and circulatory physiology · 2020
    Review
  18. Spinal cord neural network interactions: implications for sympathetic control of the porcine heart.American journal of physiology. Heart and circulatory physiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Siamak SalavatianNeurocardiology Research Program of Excellence, University of California, Los Angeles, California.
Sarah M ArdellNeurocardiology Research Program of Excellence, University of California, Los Angeles, California.
Mathew HammerNeurocardiology Research Program of Excellence, University of California, Los Angeles, California.
David GibbonsDepartment of Biomedical Sciences, East Tennessee State University, Johnson City, Tennessee.
J Andrew ArmourNeurocardiology Research Program of Excellence, University of California, Los Angeles, California.
Jeffrey L ArdellNeurocardiology Research Program of Excellence, University of California, Los Angeles, California.
University of California, Los Angeles · USTexas Cardiac Arrhythmia · USEast Tennessee State University · US

Funding

Bioelectric monitoring and control of the heartU01EB025138 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARDELL, JEFFREY L, KIPKE, DARYL R · 2017 to 2020
$4.0M
Distributed electrode system for high-fidelity cardio-neural mappingU18EB021799 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARDELL, JEFFREY L, KIPKE, DARYL R · 2015 to 2017
$640k
NIBIB NIH HHS U01 EB025138NIBIB NIH HHS U18 EB021799
6 · The paper itself

Abstract

Aberrant afferent signaling drives adverse remodeling of the cardiac nervous system in ischemic heart disease. The study objective was to determine whether thoracic spinal dorsal column stimulation (SCS) modulates cardiac afferent sensory transduction of the ischemic ventricle. In anesthetized canines (

Indexed as

ReflexSensory Receptor CellsSpinal Cord StimulationAction PotentialsAnimalsDisease Models, AnimalDogsFemaleGanglia, SpinalHeart VentriclesMaleMyocardial InfarctionVentricular Fibrillationcardiac afferent neurondorsal root ganglionmyocardial ischemiaspinal cord stimulationsympathetic

Identifiers

PMID31538809
PMCPMC6879916
OpenAlexW2973549443

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.