Evidence map›Paper›PMID 31538606›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2019

Quantitative Evaluation of the Function of the Sensory Nerve Fibers of the Palate in Patients With Obstructive Sleep Apnea.

Yunsong An, Yanru Li, Wei Chang, Fei Gao, Xiu Ding, Wen Xu, Demin Han

Registry-linked trialOpen access · bronzeAbstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03506178 (The Effects of Nasal Airflow on Upper Airway Dilator Muscles During Sleep), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03506178 naunknown statusnot on this map

The Effects of Nasal Airflow on Upper Airway Dilator Muscles During Sleep

TypeinterventionalSponsorBeijing Tongren HospitalRan2017 to 2018Enrolled30ConditionsObstructive Sleep ApneaArmsOxymetazoline Nasal Spray, Menthol Nasal Spray, Normal saline Nasal Spray, Nasal mask with partly blocked
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Role of Sensory Nerves in Pulmonary Fibrosis.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yunsong AnDepartment of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University; State Key Laboratory of Otolaryngology Head and Neck Surgery of Ministry of Education, Beijing, China.
Yanru LiDepartment of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University; State Key Laboratory of Otolaryngology Head and Neck Surgery of Ministry of Education, Beijing, China.
Wei ChangDepartment of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University; State Key Laboratory of Otolaryngology Head and Neck Surgery of Ministry of Education, Beijing, China.
Fei GaoDepartment of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University; State Key Laboratory of Otolaryngology Head and Neck Surgery of Ministry of Education, Beijing, China.
Xiu DingDepartment of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University; State Key Laboratory of Otolaryngology Head and Neck Surgery of Ministry of Education, Beijing, China.
Wen XuDepartment of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University; State Key Laboratory of Otolaryngology Head and Neck Surgery of Ministry of Education, Beijing, China.
Demin HanDepartment of Otolaryngology Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University; State Key Laboratory of Otolaryngology Head and Neck Surgery of Ministry of Education, Beijing, China.
Beijing Tongren Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

objectivesTo quantitatively evaluate the functional integrity of sensory nerve fibers of the palate in patients with obstructive sleep apnea (OSA) using the Neurometer system.

methodsA total of 32 patients with OSA and 18 healthy control patients were included in the study. All participants were selected based on medical history, physical examination, and nocturnal polysomnography (PSG) and divided into two groups. The palatal sensory status of participants was examined with a Neurometer current perception threshold (CPT) system. The system was used to deliver an electrical stimulus at three different frequencies (2,000 Hz, 250 Hz, and 5 Hz) by an investigator blinded to the PSG results.

resultsThere were no significant differences in the CPT values of the hard palate between the patients with OSA and control patients at any of the three stimulation frequencies. The differences in the CPT values of the soft palate between these groups failed to show any statistical significance at 250 Hz and 5 Hz. However, the patients with OSA showed significantly higher CPT values of the soft palate at 2,000 Hz than the age-matched healthy control patients (256.56 ± 129.34 versus 372.13 ± 152.06; P = .009).

conclusionsOur study revealed an impairment of 2,000 Hz-related sensory nerve function of the soft palate among patients with OSA. The CPT test could be a useful tool for the quantitative and selective assessment of the sensory nerve function in patients with OSA. Additional research is required to evaluate the different types of sensory nerve dysfunctions among such patients. CLINICAL

trial registrationRegistry: ClinicalTrials.gov; Title: The Effects of Nasal Airflow on Upper Airway Dilator Muscles During Sleep; Identifier: NCT03506178; URL: https://clinicaltrials.gov/ct2/show/NCT03506178. CITATION: An Y, Li Y, Chang W, Gao F, Ding X, Xu W, Han D. Quantitative evaluation of the function of the sensory nerve fibers of the palate in patients with obstructive sleep apnea. J Clin Sleep Med. 2019;15(9):1347-1353.

Indexed as

AdultElectric StimulationEvaluation Studies as TopicFemaleHumansMaleNerve FibersPalate, SoftPolysomnographySleep Apnea, Obstructiveobstructive sleep apneapolysomnographysensory nerve fiber

Identifiers

PMID31538606
PMCPMC6760391
OpenAlexW2972899172

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.