Evidence map›Paper›PMID 31538530›Full record

ArticleRNA biology2020

Organ-specific small non-coding RNA responses in domestic (Sudani) ducks experimentally infected with highly pathogenic avian influenza virus (H5N1).

Mohamed Samir, Ramon O Vidal, Fatma Abdallah, Vincenzo Capece, Frauke Seehusen, Robert Geffers, Ashraf Hussein, Ahmed A H Ali, Stefan Bonn, Frank Pessler

Open access · bronzeAbstract read
In one paragraph

Article in RNA biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Mohamed SamirDepartment of Zoonoses, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.ORCID 0000-0002-1166-0480
Ramon O VidalGroup of Computational Systems Biology, German Center for Neurodegenerative Diseases, Goettingen, Germany.
Fatma AbdallahDepartment of Virology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.ORCID 0000-0003-2226-4632
Vincenzo CapeceGroup of Computational Systems Biology, German Center for Neurodegenerative Diseases, Goettingen, Germany.
Frauke SeehusenDepartment of Pathology, University of Veterinary Medicine (TiHo), Hannover, Germany.
Robert GeffersGenome Analytics, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Ashraf HusseinDepartment of Avian and Rabbit Medicine, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.
Ahmed A H AliDepartment of Virology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.ORCID 0000-0003-1214-1700
Stefan BonnGroup of Computational Systems Biology, German Center for Neurodegenerative Diseases, Goettingen, Germany.ORCID 0000-0003-4366-5662
Frank PesslerResearch Group Biomarkers for Infectious Diseases, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany.ORCID 0000-0002-3434-2311
Zagazig University · EGHelmholtz Centre for Infection Research · DEGerman Center for Neurodegenerative Diseases · DEMax Delbrück Center · DEUniversität Hamburg · DEUniversity of Veterinary Medicine Hannover, Foundation · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The duck represents an important reservoir of influenza viruses for transmission to other avian and mammalian hosts, including humans. The increased pathogenicity of the recently emerging clades of highly pathogenic avian influenza (HPAI) viruses of the H5N1 subtype in ducks features systemic viral spread and organ-to-organ variation in viral transcription and tissue damage. We previously reported that experimental infection of Sudani ducks (

Indexed as

AnimalsChromosome MappingDucksGene Expression ProfilingHost-Pathogen InteractionsInfluenza A Virus, H5N1 SubtypeInfluenza in BirdsMicroRNAsOrgan SpecificityRNA, Small UntranslatedMicroRNAsRNA, Small UntranslatedAvian influenza virusmicroRNAPIWI-interacting RNAsmall nuclear RNAsmall nucleolar RNA

Identifiers

PMID31538530
PMCPMC6948974
OpenAlexW2973430784

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.