ArticleHeliyon2019
Physicochemical properties of alpha-mangostin loaded nanomeulsions prepared by ultrasonication technique.
Article in Heliyon, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Formulation of bacterial cellulose nanofibrils incorporated with xanthone as functional green ingredients for cosmeceutical products.Scientific reports · 2026Article
- Alpha-Mangostin: A Review of Current Research on Its Potential as a Novel Antimicrobial and Anti-Biofilm Agent.International journal of molecular sciences · 2025Review
- Characterization of Alpha Mangostin Loaded-Mesoporous Silica Nanoparticle and the Impact on Dissolution and Physical Stability.Nanotechnology, science and applications · 2025Article
- Can α-Mangostin and Photodynamic Therapy Support Ciprofloxacin in the Inactivation of UropathogenicInternational journal of molecular sciences · 2024Article
- A Mechanistic Review on Protective Effects of Mangosteen and its Xanthones Against Hazardous Materials and Toxins.Current neuropharmacology · 2024Review
- Recovery and partial isolation of ⍺-mangostin from mangosteen pericarpsvia sequential extraction and precipitation.PloS one · 2024Article
- Cytotoxicity Enhancement of α-Mangostin with Folate-Conjugated Chitosan Nanoparticles in MCF-7 Breast Cancer Cells.Molecules (Basel, Switzerland) · 2023Article
- Article
- Cytotoxicity Enhancement in MCF-7 Breast Cancer Cells with Depolymerized Chitosan Delivery of α-Mangostin.Polymers · 2022Article
- Fabrication and Biological Assessment of Antidiabetic α-Mangostin Loaded Nanosponges: In Vitro, In Vivo, and In Silico Studies.Molecules (Basel, Switzerland) · 2021Article
- α-Mangostin Nanoparticles Cytotoxicity and Cell Death Modalities in Breast Cancer Cell Lines.Molecules (Basel, Switzerland) · 2021Review
- Article
- α-Mangostin Induces Apoptosis and Inhibits Metastasis of Breast Cancer Cells via Regulating RXRα-AKT Signaling Pathway.Frontiers in pharmacology · 2021Article
- Natural Xanthones and Skin Inflammatory Diseases: Multitargeting Mechanisms of Action and Potential Application.Frontiers in pharmacology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
hypothesisAlpha-mangostin (AMG) is a natural compound possessing strong antibacterial activity. Because of its poor water solubility, the formulations of AMG usually require high concentrations of solubilizers leading limitation for using in some clinical applications. Thus, the novel formulation of topical nanoemulsion (NE) containing AMG (AMG-NE) with optimal content of the oil phase and surfactants was developed. EXPERIMENTS: AMG was extracted, purified and used as an active ingredient of AMG-NE. Blank NEs (NEs without AMG) with varying in contents of the oil phase and surfactants and AMG-NE were prepared by the ultrasonication technique. They were investigated their physicochemical properties including antibacterial activity against
findingsBlank NEs and AMG-NE had droplet size in a range of nanometer and negative value of zeta potential. The droplet size, polydispersity index and zeta potential of blank NEs were affected by formulation compositions and sonication intensities. AMG could be loaded into a representative Blank NE at a maximum concentration of 0.2% w/w and did not cause significant changes in physicochemical properties. AMG-NE showed the antibacterial activity against
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.