Evidence map›Paper›PMID 31537860›Full record

ArticleScientific reports2019

Genomic diversity, linkage disequilibrium and selection signatures in European local pig breeds assessed with a high density SNP chip.

M Muñoz, R Bozzi, J García-Casco, Y Núñez, A Ribani, O Franci, F García, M Škrlep, G Schiavo, S Bovo and 21 more

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

M MuñozDepartamento Mejora Genética Animal, INIA, Madrid, Spain.ORCID http://orcid.org/0000-0002-7018-6977
R BozziDAGRI, Animal Science Section, Università degli Studi di Firenze, Firenze, Italy.ORCID http://orcid.org/0000-0001-8854-0834
J García-CascoDepartamento Mejora Genética Animal, INIA, Madrid, Spain.
Y NúñezDepartamento Mejora Genética Animal, INIA, Madrid, Spain.
A RibaniDepartment of Agricultural and Food Sciences, University of Bologna, Bologna, Italy.
O FranciDAGRI, Animal Science Section, Università degli Studi di Firenze, Firenze, Italy.
F GarcíaDepartamento Mejora Genética Animal, INIA, Madrid, Spain.
M ŠkrlepKmetijski inštitut Slovenije, Hacquetova ulica 17, SI-1000, Ljubljana, Slovenia.
G SchiavoDepartment of Agricultural and Food Sciences, University of Bologna, Bologna, Italy.
S BovoDepartment of Agricultural and Food Sciences, University of Bologna, Bologna, Italy.ORCID http://orcid.org/0000-0002-5712-8211
V J UtzeriDepartment of Agricultural and Food Sciences, University of Bologna, Bologna, Italy.
R CharnecaInstituto de Ciências Agrárias e Ambientais Mediterrânicas (ICAAM), Universidade de Évora, Évora, Portugal.
J M MartinsInstituto de Ciências Agrárias e Ambientais Mediterrânicas (ICAAM), Universidade de Évora, Évora, Portugal.ORCID http://orcid.org/0000-0003-3616-8406
R QuintanillaIRTA, Programa de Genética y Mejora Animal, Barcelona, Spain.
J TibauIRTA, Programa de Genética y Mejora Animal, Barcelona, Spain.
V MargetaFaculty of Agrobiotechnical Sciences Osijek, University of Osijek, Osijek, Croatia.
I Djurkin-KušecFaculty of Agrobiotechnical Sciences Osijek, University of Osijek, Osijek, Croatia.ORCID http://orcid.org/0000-0002-1363-8447
M J MercatIFIP - Institut du Porc, Le Rheu, France.
J RiquetINRA, Génétique Physiologie et Système d'Elevage, Castanet-Tolosan, France.
J EstelléGABI, INRA, AgroParisTech, Université Paris-Saclay, Jouy-en-Josas, France.ORCID http://orcid.org/0000-0002-6241-1732
C ZimmerBäuerliche Erzeugergemeinschaft Schwäbisch Hall, Wolpertshausen, Germany.
V RazmaiteAnimal Science Institute, Lithuanian University of Health Sciences, Baisogala, Lithuania.ORCID http://orcid.org/0000-0001-9006-5761
J P AraujoCentro de Investigação de Montanha (CIMO), Instituto Politécnico de Viana do Castelo, Escola Superior Agrária, Ponte de Lima, Portugal.
Č RadovićInstitute for Animal Husbandry-Pig Research Department, Autoput for Zagreb 16, 11080, Belgrade-Zemun, Serbia.
R SavićUniversity of Belgrade, Faculty of agriculture, Nemanjina 6, 11080, Belgrade-Zemun, Serbia.ORCID http://orcid.org/0000-0003-2131-5303
D KarolyiDepartment of Animal Science, University of Zagreb, Faculty of Agriculture, Zagreb, Croatia.ORCID http://orcid.org/0000-0003-0409-9071
M GalloAssociazione Nazionale Allevatori Suini (ANAS), Roma, Italy.
M Čandek-PotokarKmetijski inštitut Slovenije, Hacquetova ulica 17, SI-1000, Ljubljana, Slovenia.ORCID http://orcid.org/0000-0003-0231-126X
A I FernándezDepartamento Mejora Genética Animal, INIA, Madrid, Spain.
L FontanesiDepartment of Agricultural and Food Sciences, University of Bologna, Bologna, Italy.ORCID http://orcid.org/0000-0001-7050-3760
C ÓviloDepartamento Mejora Genética Animal, INIA, Madrid, Spain. ovilo@inia.es.ORCID http://orcid.org/0000-0002-5738-8435

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic characterization of local breeds is essential to preserve their genomic variability, to advance conservation policies and to contribute to their promotion and sustainability. Genomic diversity of twenty European local pig breeds and a small sample of Spanish wild pigs was assessed using high density SNP chips. A total of 992 DNA samples were analyzed with the GeneSeek Genomic Profiler (GGP) 70 K HD porcine genotyping chip. Genotype data was employed to compute genetic diversity, population differentiation and structure, genetic distances, linkage disequilibrium and effective population size. Our results point out several breeds, such as Turopolje, Apulo Calabrese, Casertana, Mora Romagnola and Lithuanian indigenous wattle, having the lowest genetic diversity, supported by low heterozygosity and very small effective population size, demonstrating the need of enhanced conservation strategies. Principal components analysis showed the clustering of the individuals of the same breed, with few breeds being clearly isolated from the rest. Several breeds were partially overlapped, suggesting genetic closeness, which was particularly marked in the case of Iberian and Alentejana breeds. Spanish wild boar was also narrowly related to other western populations, in agreement with recurrent admixture between wild and domestic animals. We also searched across the genome for loci under diversifying selection based on F

Indexed as

AnimalsAnimals, DomesticBreedingGenetics, PopulationGenetic VariationGenomeGenomicsGenotypeLinkage DisequilibriumOligonucleotide Array Sequence AnalysisPhenotypePolymorphism, Single NucleotidePopulation DensityPrincipal Component AnalysisSwine

Identifiers

PMID31537860
PMCPMC6753209

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.