Evidence map›Paper›PMID 31537710›Full record

ArticleThe Journal of cell biology2019

Eph receptors and ephrins engage in cellular cannibalism.

Elena B Pasquale

Open access · bronzeAbstract readComment
In one paragraph

Article in The Journal of cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Elena B PasqualeCancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA elenap@sbpdiscovery.org.ORCID 0000-0002-5076-4848
Sanford Burnham Prebys Medical Discovery Institute · US

Funding

Ligand functional selectivity in EphA2 receptor signalingR01GM131374 · NIGMS · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI Kalina Hristova, ELENA B PASQUALE · 2019 to 2026
$3.8M
Cyclic EphA4 peptide antagonists for neuroprotection in ALSR01NS087070 · NINDS · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI PASQUALE, ELENA B · 2014 to 2018
$3.5M
NIGMS NIH HHS R01 GM131374NINDS NIH HHS R01 NS087070
6 · The paper itself

Abstract

Eph receptors bind ephrins on neighboring cells, oligomerizing into adhesive complexes that recruit signaling molecules. Execution of their signature repulsive program then generates pulling forces, enabling a cell to engulf a piece of another cell. New mechanistic insights by Gong et al. (2019.

Indexed as

EphrinsReceptors, Eph FamilyCytophagocytosisProtein BindingSignal TransductionEphrinsReceptors, Eph Family

Identifiers

PMID31537710
PMCPMC6781436
OpenAlexW2974744343

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.