Evidence map›Paper›PMID 31537593›Full record

ArticleBMJ case reports2019

An unusual presentation of ACE inhibitor-induced visceral angioedema.

Amanda Jayne Krause, Naiya Balubhai Patel, Jennifer Morgan

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Diarrhea induced by angiotensin-converting enzyme inhibitors.Canadian family physician Medecin de famille canadien · 2026
    Article
  4. Review
  5. Bradykinin-Mediated Angioedema Induced by Drugs.Journal of clinical medicine · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Amanda Jayne KrauseInternal Medicine, McGaw Medical Center of Northwestern University, Chicago, Illinois, USA.
Naiya Balubhai PatelInternal Medicine, McGaw Medical Center of Northwestern University, Chicago, Illinois, USA.
Jennifer MorganInternal Medicine, McGaw Medical Center of Northwestern University, Chicago, Illinois, USA.
Northwestern University · USNorthwestern Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ACE inhibitors (ACEi) are common anti-hypertensive drugs that can cause angioedema. Though classic, or facial angioedema is rare, visceral angioedema is even less common. When angioedema occurs, it typically presents early, within 30 days of initiating therapy. Visceral angioedema most commonly presents with nausea, emesis, abdominal pain and diarrhoea, and thus is often mistaken for an episode of gastroenteritis. When a CT scan is obtained, it typically shows characteristic findings, including ascetic fluid, mild mesenteric oedema and thickening of the small bowel. In this case report, we present a patient who did not experience her first episode of visceral angioedema until after she had been on ACEi therapy for 5-7 years. In addition, she experienced recurrent episodes of visceral angioedema that were separated by approximately 4 years at a time. Both of these features make for a particularly unique presentation.

Indexed as

Abdominal PainAngioedemaAngiotensin-Converting Enzyme InhibitorsAnti-Allergic AgentsDiagnosis, DifferentialDiarrheaFemaleGlucocorticoidsHistamine H2 AntagonistsHumansLisinoprilMiddle AgedNauseaTomography, X-Ray ComputedTreatment OutcomeVisceraAngiotensin-Converting Enzyme InhibitorsAnti-Allergic AgentsGlucocorticoidsHistamine H2 AntagonistsLisinoprilallergyasthmacardiovascular systemdrugs: gastrointestinal systemunwanted effects/adverse reactions

Identifiers

PMID31537593
PMCPMC6754668
OpenAlexW2974577841

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.