Evidence map›Paper›PMID 31537571›Full record

ArticleBMJ open2019

Are socioenvironmental factors associated with psychotic symptoms in people with first-episode psychosis? A cross-sectional study of a West London clinical sample.

Marc S Tibber, James B Kirkbride, Stanley Mutsatsa, Isobel Harrison, Thomas R E Barnes, Eileen M Joyce, Vyv Huddy

Abstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. A meta-analysis of the role of neighborhood deprivation in psychotic disorders.Social psychiatry and psychiatric epidemiology · 2025
    Pooled it
  2. Pooled it
  3. Social Fragmentation and Schizophrenia: A Systematic Review.The Journal of clinical psychiatry · 2021
    Pooled it
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Urbanicity and psychotic disorders: Facts and hypotheses.Dialogues in clinical neuroscience · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Association of rs4680Frontiers in psychiatry · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marc S TibberDepartment of Clinical, Educational and Health Psychology, University College London, London, UK m.tibber@ucl.ac.uk.
James B KirkbrideDivision of Psychiatry, University College London, London, UK.
Stanley MutsatsaSchool of Health Sciences, City, University of London, London, UK.
Isobel HarrisonDivision of Psychiatry, University College London, London, UK.
Thomas R E BarnesDivision of Psychiatry, Imperial College London, London, UK.
Eileen M JoyceUCL Queen Square Institute of Neurology, University College London, London, UK.
Vyv HuddyClinical Psychology Unit, Department of Psychology, University of Sheffield, Sheffield, UK.

Funding

Wellcome TrustWellcome Trust 064607/Z/01/ZWellcome Trust 101272/Z/13/Z
6 · The paper itself

Abstract

objectivesTo determine whether neighbourhood-level socioenvironmental factors including deprivation and inequality predict variance in psychotic symptoms after controlling for individual-level demographics.

designA cross-sectional design was employed.

settingData were originally collected from secondary care services within the UK boroughs of Ealing, Hammersmith and Fulham, Wandsworth, Kingston, Richmond, Merton, Sutton and Hounslow as part of the West London First-Episode Psychosis study.

participantsComplete case analyses were undertaken on 319 participants who met the following inclusion criteria: aged 16 years or over, resident in the study's catchment area, experiencing a first psychotic episode, with fewer than 12 weeks' exposure to antipsychotic medication and sufficient command of English to facilitate assessment. OUTCOME MEASURES: Symptom dimension scores, derived from principal component analyses of the Scale for the Assessment of Positive Symptoms and Scale for the Assessment of Negative Symptoms, were regressed on neighbourhood-level predictors, including population density, income deprivation, income inequality, social fragmentation, social cohesion, ethnic density and ethnic fragmentation, using multilevel regression. While age, gender and socioeconomic status were included as individual-level covariates, data on participant ethnicity were not available.

resultsHigher income inequality was associated with lower negative symptom scores (coefficient=-1.66, 95% CI -2.86 to -0.46, p<0.01) and higher levels of ethnic segregation were associated with lower positive symptom scores (coefficient=-2.32, 95% CI -4.17 to -0.48, p=0.01) after adjustment for covariates.

conclusionsThese findings provide further evidence that particular characteristics of the environment may be linked to specific symptom clusters in psychosis. Longitudinal studies are required to begin to tease apart the underlying mechanisms involved as well as the causal direction of such associations.

Indexed as

Social ClassSocial Determinants of HealthAdultCross-Sectional StudiesEthnicityFemaleHumansIncomeLondonMalePopulation DensityPovertyPsychotic DisordersResidence CharacteristicsSocial EnvironmentSocial ProblemsAdult psychiatryDeprivationEpidemiologyInequalitySchizophrenia & psychotic disordersSocial capital

Identifiers

PMID31537571
PMCPMC6756588

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.