Evidence map›Paper›PMID 31537456›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2019

AAV6 Is Superior to Clade F AAVs in Stimulating Homologous Recombination-Based Genome Editing in Human HSPCs.

Amanda M Dudek, Matthew H Porteus

Abstract readLetterComment
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Understanding and overcoming adverse consequences of genome editing on hematopoietic stem and progenitor cells.Molecular therapy : the journal of the American Society of Gene Therapy · 2021
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Reply to "Efficient Nuclease-free HR by Clade F AAV Requires High MOIs with High Quality Vectors".Molecular therapy : the journal of the American Society of Gene Therapy · 2019
    Article
  12. Reply to "Efficient Nuclease-free HR by Clade F AAV Requires High MOIs with High Quality Vectors".Molecular therapy : the journal of the American Society of Gene Therapy · 2019
    Article
  13. Efficient Nuclease-free HR by Clade F AAV Requires High MOIs with High Quality Vectors.Molecular therapy : the journal of the American Society of Gene Therapy · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Amanda M DudekDepartment of Pediatrics, Stanford University, Stanford, CA 94305, USA.
Matthew H PorteusDepartment of Pediatrics, Stanford University, Stanford, CA 94305, USA. Electronic address: mporteus@stanford.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene EditingHomologous RecombinationDependovirusDNA BreaksGenome, HumanHumans

Identifiers

PMID31537456
PMCPMC6822226

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.