Evidence map›Paper›PMID 31537410›Full record

ArticleJournal of vascular and interventional radiology : JVIR2020

Application of Trifluoroacetic Acid as a Theranostic Agent for Chemical Ablation of Solid Tissue.

Samuel A Einstein, Emily A Thompson, Chunxiao Guo, Elizabeth M Whitley, James A Bankson, Erik N K Cressman

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of vascular and interventional radiology : JVIR, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Samuel A EinsteinDepartment of Imaging Physics, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit 1471; Houston, TX, 77030.
Emily A ThompsonDepartment of Imaging Physics, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit 1471; Houston, TX, 77030.
Chunxiao GuoDepartment of Interventional Radiology, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit 1471; Houston, TX, 77030.
Elizabeth M WhitleyDepartment of Veterinary Medicine & Surgery, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit 1471; Houston, TX, 77030.
James A BanksonDepartment of Imaging Physics, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit 1471; Houston, TX, 77030.
Erik N K CressmanDepartment of Interventional Radiology, The University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Unit 1471; Houston, TX, 77030. Electronic address: ECressman@mdanderson.org.
The University of Texas MD Anderson Cancer Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
Simultaneous Thermal and Osmotic Stresses in Tumor Ablation: Imaging and BiologyR01CA201127 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI CRESSMAN, ERIK N · 2016 to 2020
$2.3M
NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA201127
6 · The paper itself

Abstract

purposeTo evaluate trifluoroacetic acid (TFA) as a theranostic chemical ablation agent and determine the efficacy of TFA for both noninvasive imaging and tissue destruction. MATERIALS AND

methodsFluorine-19 magnetic resonance imaging (

resultsThe optimal

conclusionsTFA was determined to be a theranostic agent for chemical ablation of solid tissue. Ablation was both efficacious and imageable in ex vivo healthy tissue, even at low concentrations or with high temporal resolution.

Indexed as

Ablation TechniquesAnimalsFluorineLiverMagnetic Resonance Imaging, CineSus scrofaTrifluoroacetic AcidFluorineTrifluoroacetic Acid

Identifiers

PMID31537410
PMCPMC6926148
OpenAlexW2973509576

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.