Evidence map›Paper›PMID 31536841›Full record

ArticleActa biomaterialia2019

Incorporation of a silicon-based polymer to PEG-DA templated hydrogel scaffolds for bioactivity and osteoinductivity.

Michael T Frassica, Sarah K Jones, Patricia Diaz-Rodriguez, Mariah S Hahn, Melissa A Grunlan

Open access · greenAbstract read
In one paragraph

Article in Acta biomaterialia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
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  6. Titania (TiONanoscale · 2024
    Article
  7. Journal of materials chemistry. B · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Michael T FrassicaDepartment of Biomedical Engineering, Texas A&M University, College Station, TX 77843-3120, USA.
Sarah K JonesDepartment of Biomedical Engineering, Texas A&M University, College Station, TX 77843-3120, USA.
Patricia Diaz-RodriguezDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180-31590, USA.
Mariah S HahnDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180-31590, USA.
Melissa A GrunlanDepartment of Biomedical Engineering, Texas A&M University, College Station, TX 77843-3120, USA; Department of Materials Science & Engineering, Texas A&M University, College Station, TX 77843-3003, USA; Department of Chemistry, Texas A&M University, College Station, TX 77843-3255, USA. Electronic address: mgrunlan@tamu.edu.
Texas A&M University · USRensselaer Polytechnic Institute · US

Funding

Bioactive, "Self-fitting" Shape Memory Polymer (SMP) Scaffolds to Treat Cranial Bone DefectsR01DE025886 · NIDCR · TEXAS ENGINEERING EXPERIMENT STATION · PI GRUNLAN, MELISSA · 2017 to 2020
$1.8M
NIDCR NIH HHS R01 DE025886
6 · The paper itself

Abstract

A scaffold that is inherently bioactive, osteoinductive and osteoconductive may guide mesenchymal stem cells (MSCs) to regenerate bone tissue in the absence of exogenous growth factors. Previously, we established that hydrogel scaffolds formed by crosslinking methacrylated star poly(dimethylsiloxane) (PDMS

Indexed as

Biocompatible MaterialsBone Marrow CellsBone RegenerationCell DifferentiationCell LineageElasticityHumansHydrogelsMagnetic Resonance SpectroscopyMaterials TestingMesenchymal Stem CellsOsteoblastsOsteogenesisPolyethylene GlycolsRegenerative MedicineSaltsBiocompatible MaterialsHydrogelspoly(ethylene glycol)diacrylatePolyethylene GlycolsSaltsSiliconSolventsPoly(dimethylsiloxane)Poly(ethylene glycol)Salt templatingScaffoldTissue engineering

Identifiers

PMID31536841
PMCPMC6936328
OpenAlexW2974756879

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.