ArticleUrology2019
New Persistent Opioid Use After Outpatient Ureteroscopy for Upper Tract Stone Treatment.
Article in Urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05507554 (Effectiveness of Different Postoperative Analgesics Use in the Management of Acute Pain After Ureteroscopy.), which is not on this map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of Different Postoperative Analgesics Use in the Management of Acute Pain After Ureteroscopy.
Who cites it
17 citing papers in PubMed, 44 citations in OpenAlex.
- Optimizing pain management following kidney stone surgery: can we avoid narcotics?World journal of urology · 2022Trial
- Postoperative pain management after ureteroscopy: focused approaches to reducing opiate dependence.Pain management · 2025Review
- Questionable role of opioids for analgesia in renal colic and its urological interventions.BJUI compass · 2025Review
- A prospective study to determine the safety and feasibility of opioid-free discharge after percutaneous nephrolithotomy.Translational andrology and urology · 2025Article
- Genetic Associations of Persistent Opioid Use After Surgery Point to OPRM1 but Not Other Opioid-Related Loci as the Main Driver of Opioid Use Disorder.Genetic epidemiology · 2025Article
- Exploring the role of perioperative pregabalin in ureteroscopy enhanced recovery after surgery (ERAS) protocols.Translational andrology and urology · 2024Article
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- Opioids in Urology: How Well Are We Preventing Opioid Dependence and How Can We Do Better?Health psychology research · 2022Article
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- Opioid Addiction and Opioid Receptor Dimerization: Structural Modeling of the OPRD1 and OPRM1 Heterodimer and Its Signaling Pathways.International journal of molecular sciences · 2021Article
- Postoperative opioid-free ureteroscopy discharge: A quality initiative pilot protocol.Current urology · 2021Article
- Evaluating the opioid epidemic: a urologist's promise to curb the crisis.Translational andrology and urology · 2021Article
- Long-acting liposomal bupivacaine and postoperative opioid use after Peyronie's disease surgery: a pilot study.Translational andrology and urology · 2021Article
- Increased risk of new persistent opioid use in pediatric and young adult patients with kidney stones.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2020Article
- Opioid prescribing after urologic surgery: we are part of the problem and part of the solution-an invited commentary on "an opioid prescription for men undergoing minor urologic surgery is associated with an increased risk of new persistent opioid use".Translational andrology and urology · 2020Article
- Improving care to decrease stone recurrence and opioid use.Nature reviews. Urology · 2020Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo measure the incidence of persistent opioid use following ureteroscopy (URS). Over 100 Americans die every day from opioid overdose. Recent studies suggest that many opioid addictions surface after surgery.
methodsUsing claims data, we identified adults who underwent outpatient URS for treatment of upper tract stones between January 2008 and December 2016 and filled an opioid prescription attributable to URS. We then measured the rate of new persistent opioid use-defined as continued use of opioids 91-180 days after URS among those who were previously opioid-naive. Finally, we fit multivariable models to assess whether new persistent opioid use was associated with the amount of opioid prescribed at the time of URS.
resultsIn total, 27,740 patients underwent outpatient URS, 51.2% of whom were opioid-naïve. Nearly 1 in 16 (6.2%) opioid-naïve patients developed new persistent opioid use after URS. Six months following surgery, beneficiaries with new persistent opioid use continued to fill prescriptions with daily doses of 4.2 oral morphine equivalents. Adjusting for measured sociodemographic and clinical differences, patients in the highest tercile of opioids prescribed at the time of URS had 69% higher odds of new persistent opioid use compared to those in the lowest tercile (odds ratio, 1.69; 95% CI, 1.41-2.03).
conclusionNearly 1 in 16 opioid-naive patients develop new persistent opioid use after URS. New persistent opioid use is associated with the amount of opioid prescribed at the time of URS. Given these findings, urologists should re-evaluate their post-URS opioid prescribing patterns.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.