Evidence map›Paper›PMID 31536735›Full record

ArticleBehavioural brain research2020

The amygdala differentially regulates defensive behaviors evoked by CO

R J Taugher, B J Dlouhy, C J Kreple, A Ghobbeh, M M Conlon, Y Wang, J A Wemmie

Open access · greenAbstract read
In one paragraph

Article in Behavioural brain research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Article
  3. Locus coeruleus noradrenaline depletion and its differential impact on COProgress in neuro-psychopharmacology & biological psychiatry · 2024
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Chemoreceptor mechanisms regulating COThe Journal of physiology · 2021
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

R J TaugherDepartment of Psychiatry, University of Iowa, Iowa City, IA, USA; Department of Veterans Affairs Medical Center, Iowa City, IA, USA.
B J DlouhyDepartment of Neurosurgery, University of Iowa, Iowa City, IA, USA; Pappajohn Biomedical Institute, University of Iowa, Iowa City, IA, USA; Iowa Neuroscience Institute, University of Iowa, Iowa City, IA, USA.
C J KrepleDepartment of Molecular Physiology and Biophysics, University of Iowa, Iowa City, IA, USA; Medical Scientist Training Program, University of Iowa, Iowa City, IA, USA.
A GhobbehDepartment of Psychiatry, University of Iowa, Iowa City, IA, USA; Department of Veterans Affairs Medical Center, Iowa City, IA, USA.
M M ConlonDepartment of Psychiatry, University of Iowa, Iowa City, IA, USA; Department of Veterans Affairs Medical Center, Iowa City, IA, USA.
Y WangDepartment of Psychiatry, University of Iowa, Iowa City, IA, USA.
J A WemmieDepartment of Psychiatry, University of Iowa, Iowa City, IA, USA; Interdisciplinary Graduate Program in Neuroscience, University of Iowa, Iowa City, IA, USA. Electronic address: john-wemmie@uiowa.edu.
University of Iowa · US

Funding

The Iowa Neuroscience Specialty Program in Research Education (INSPIRE)T32MH019113 · NIMH · UNIVERSITY OF IOWA · PI HANNA E STEVENS, John A Wemmie · 1991 to 2026
$5.6M
Interdisciplinary Training Program in Pain ResearchT32NS045549 · NINDS · UNIVERSITY OF IOWA · PI KATHLEEN A SLUKA, Yuriy M Usachev · 2004 to 2026
$3.7M
Regulation of Cerebral Blood Flow by Acid-Sensing Ion Channels (ASICs)R01HL113863 · NHLBI · UNIVERSITY OF IOWA · PI FARACI, FRANK M, WEMMIE, JOHN A · 2012 to 2016
$1.9M
Modeling CO2-evoked fear in mice: role of acid-sensing ion channelsR01MH085724 · NIMH · UNIVERSITY OF IOWA · PI WEMMIE, JOHN A · 2009 to 2013
$1.8M
Basolateral amygdala circuits in defensive behavior regulationR01MH113325 · NIMH · UNIVERSITY OF IOWA · PI WEMMIE, JOHN A · 2018 to 2022
$1.8M
Investigating a novel regulatory pathway for opioid-induced synaptic plasticity and behaviorI01BX004440 · VA · IOWA CITY VA MEDICAL CENTER · PI John A Wemmie · 2020 to 2026
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BLRD VA I01 BX004440NHLBI NIH HHS R01 HL113863NIMH NIH HHS R01 MH085724NIMH NIH HHS R01 MH113325NIMH NIH HHS T32 MH019113NINDS NIH HHS T32 NS045549
6 · The paper itself

Abstract

CO

Indexed as

Behavior, AnimalLocomotionAmygdalaAnimalsCarbon DioxideFearFreezing Reaction, CatalepticMiceMice, Inbred C57BLPeriaqueductal GrayCarbon DioxideAmygdalaCarbon dioxidePanicPeriacqueductal gray

Identifiers

PMID31536735
PMCPMC6829583
OpenAlexW2974834675

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.