Evidence map›Paper›PMID 31536120›Full record

ArticleThe Journal of infectious diseases2020

Prevalence, Incidence, and Clearance of Human Papillomavirus Types Covered by Current Vaccines in Men With Human Immunodeficiency Virus in the SUN Study.

Pragna Patel, Tim Bush, Lois Conley, Elizabeth R Unger, Teresa M Darragh, Keith Henry, Gerome Escota, John T Brooks, Erna Milunka Kojic

Abstract read
In one paragraph

Article in The Journal of infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Oncogenic Oral Human Papillomavirus Clearance Patterns over 10 Years.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
  5. Genital Human Papillomavirus Prevalence and Genotyping Among Males in Putuo District of Shanghai, China 2015-2019.Medical science monitor : international medical journal of experimental and clinical research · 2021
    Article
  6. Article
  7. Another Call for Widespread Human Papillomavirus Vaccination.The Journal of infectious diseases · 2020
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Pragna PatelCenters for Disease Control and Prevention, Atlanta, Georgia.
Tim BushCenters for Disease Control and Prevention, Atlanta, Georgia.
Lois ConleyCenters for Disease Control and Prevention, Atlanta, Georgia.
Elizabeth R UngerCenters for Disease Control and Prevention, Atlanta, Georgia.
Teresa M DarraghUniversity of California, San Francisco.
Keith HenryHennepin County Medical Center, Minneapolis, Minnesota.
Gerome EscotaWashington University School of Medicine, St Louis, Missouri.
John T BrooksCenters for Disease Control and Prevention, Atlanta, Georgia.
Erna Milunka KojicMount Sinai Hospital, St Luke's, and West Hospitals, New York, New York.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundHigh-risk anal human papillomavirus (HPV) infection is prevalent among men living with human immunodeficiency virus (HIV); the association between 9-valent (9v) high-risk HPV (HR-HPV) vaccine types and abnormal cytology has not been well characterized.

methodsWe followed a prospective cohort study of persons with HIV at 7 HIV clinics in 4 US cities from March 2004 through June 2012. Annually, providers collected separate anal swabs for HPV detection and cytopathologic examination. Among men, we examined prevalence, incidence, and clearance of 9v HR-HPV vaccine types, compared with other HR types, and associations with abnormal cytology to assess potential vaccine impact.

resultsBaseline prevalence of any anal 9v HR-HPV type among men who have sex with men (MSM) and men who have sex with women (MSW) was 74% and 25% (P < .001), respectively. Among 299 MSM, abnormal cytology was detected in 161 (54%) MSM and was associated with the presence of any 9v HR-HPV (relative risk [RR], 1.8 [95% confidence interval {CI}, 1.3-2.6]; P < .001). Among 61 MSW, abnormal anal cytology was detected in 12 (20%) and was associated with the presence of any 9v HR-HPV (RR, 4.3 [95% CI, 1.6-11.5]; P < .001).

conclusionsAmong men with HIV, the prevalence of the 7 HR-HPV types in the 9v vaccine was high and was associated with abnormal cytology. These findings indicate that men with HIV could benefit from prophylactic administration of the 9v HPV vaccine.

Indexed as

Papillomavirus VaccinesAdultAlphapapillomavirusAnal CanalAnus DiseasesHIV InfectionsHumansIncidenceMaleMiddle AgedPapillomavirus InfectionsPrevalenceProspective StudiesSexual and Gender MinoritiesPapillomavirus VaccinesHIVHPVHPV vaccinehuman immunodeficiency virushuman papillomavirus

Identifiers

PMID31536120
PMCPMC11519787

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.