Evidence map›Paper›PMID 31536046›Full record

ArticleJournal of pain research2019

Effects of long-term treatment with Dienogest on the quality of life and sexual function of women affected by endometriosis-associated pelvic pain.

Salvatore Caruso, Marco Iraci, Stefano Cianci, Salvatore Giovanni Vitale, Valentina Fava, Antonio Cianci

Open access · goldAbstract read
In one paragraph

Article in Journal of pain research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 69 citations in OpenAlex.

  1. Trial
  2. Review
  3. Observational
  4. Hormonal Treatment of Endometriosis: A Narrative Review.Pharmaceuticals (Basel, Switzerland) · 2025
    Review
  5. Adenomyosis: A potential cause of surgical failure in treating dyspareunia in rectovaginal septum endometriosis.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Hormonal treatments for endometriosis: The endocrine background.Reviews in endocrine & metabolic disorders · 2022
    Review
  15. Article
  16. Article
  17. Patient-Reported Outcome Measures in Endometriosis.Journal of clinical medicine · 2021
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Salvatore CarusoDepartment of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy.
Marco IraciDepartment of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy.
Stefano CianciDepartment of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy.
Salvatore Giovanni VitaleDepartment of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy.
Valentina FavaDepartment of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy.
Antonio CianciDepartment of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy.
University of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this prospective study was to evaluate quality of life (QoL) and sexual function of women affected by endometriosis pain treated with Dienogest (DNG) for 24 months. PATIENTS AND

methodsFifty-four women constituted the study group and were given DNG 2 mg/daily; 38 women were given non-steroidal anti-inflammatory drugs (NSAIDs) and constituted the control group. To define endometriosis-associated pelvic pain, dysmenorrhea and dyspareunia the Visual Analogic Scale (VAS) was used. The Short Form-36 (SF-36), the Female Sexual Function Index (FSFI) and the Female Sexual Distress Scale (FSDS) were used to assess the QoL, sexual function and the sexual distress, respectively. The study included five follow-ups at 3, 6, 12, 18 and 24 months.

resultsSlight improvements in chronic pelvic pain, dysmenorrhea and dyspareunia were observed in the study group at 3 months (

conclusionLong-term treatment with DNG 2 mg once-daily in women with endometriosis-associated pelvic pain may have positive effects on the QoL and sexual life, confirming the observations of the previous study on the first 6 months of treatment.

Indexed as

chronic pelvic paindyspareuniaendometriosislong term dienogestquality of lifesexual life

Identifiers

PMID31536046
PMCPMC6681157
OpenAlexW2965687471

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.