Evidence map›Paper›PMID 31535974›Full record

ArticleeLife2019

RIM-BP2 primes synaptic vesicles

Marisa M Brockmann, Marta Maglione, Claudia G Willmes, Alexander Stumpf, Boris A Bouazza, Laura M Velasquez, M Katharina Grauel, Prateep Beed, Martin Lehmann, Niclas Gimber and 4 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Non-canonical function of ADAM10 in presynaptic plasticity.Cellular and molecular life sciences : CMLS · 2024
    Article
  3. RIM and RIM-Binding Protein Localize Synaptic CaV2 Channels to Differentially Regulate Transmission in Neuronal Circuits.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Molecular definition of distinct active zone protein machineries for CabioRxiv : the preprint server for biology · 2023
    Article
  9. Article
  10. Multiple pathways and independent functional pools in insulin granule exocytosis.Genes to cells : devoted to molecular & cellular mechanisms · 2023
    Review
  11. Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  12. Article
  13. Article
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  15. Article
  16. Review
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Marisa M Brockmann *Institut für Neurophysiologie, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.ORCID 0000-0002-1386-5359
Marta Maglione *Freie Universität Berlin, Institut für Biologie, Berlin, Germany.
Claudia G Willmes *DZNE, German Center for Neurodegenerative Diseases, Berlin, Germany.
Alexander StumpfNeuroscience Research Center, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Boris A BouazzaInstitut für Neurophysiologie, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Laura M VelasquezNeuroscience Research Center, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
M Katharina GrauelInstitut für Neurophysiologie, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.ORCID 0000-0003-3542-0606
Prateep BeedNeuroscience Research Center, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Martin LehmannLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany.
Niclas GimberNeuroscience Research Center, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Jan SchmoranzerNeuroCure Cluster of Excellence, Berlin, Germany.
Stephan J SigristFreie Universität Berlin, Institut für Biologie, Berlin, Germany.ORCID 0000-0002-1698-5815
Christian RosenmundInstitut für Neurophysiologie, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.ORCID 0000-0002-3905-2444
Dietmar SchmitzNeuroCure Cluster of Excellence, Berlin, Germany.
Humboldt-Universität zu Berlin · DEGerman Center for Neurodegenerative Diseases · DELeibniz-Forschungsinstitut für Molekulare Pharmakologie · DE

Funding

Deutsche Forschungsgemeinschaft EXC-2049-390688087Deutsche Forschungsgemeinschaft SFB 958 A3Deutsche Forschungsgemeinschaft SFB 958 A5Deutsche Forschungsgemeinschaft SFB 958 A6
6 · The paper itself

Abstract

All synapses require fusion-competent vesicles and coordinated Ca

Indexed as

AnimalsIntracellular Signaling Peptides and ProteinsMiceMossy Fibers, HippocampalNerve Tissue ProteinsNeuronsNeurotransmitter AgentsSynaptic VesiclesIntracellular Signaling Peptides and ProteinsNerve Tissue ProteinsNeurotransmitter AgentsRimbp2 protein, mouseUnc13a protein, mouseactive zonecalcium channelhippocampusmouseneuroscienceneurotransmitter releasevesicle priming

Identifiers

PMID31535974
PMCPMC6752948
OpenAlexW2973496478

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.