Evidence map›Paper›PMID 31535971›Full record

ArticleeLife2019

ON selectivity in the

Sebastian Molina-Obando, Juan Felipe Vargas-Fique, Miriam Henning, Burak Gür, T Moritz Schladt, Junaid Akhtar, Thomas K Berger, Marion Silies

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 48 citations in OpenAlex.

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  12. Network Statistics of the Whole-Brain Connectome ofbioRxiv : the preprint server for biology · 2024
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  13. Neuronal wiring diagram of an adult brain.bioRxiv : the preprint server for biology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Sebastian Molina-ObandoInstitute of Developmental Biology and Neurobiology, Johannes Gutenberg-Universität Mainz, Mainz, Germany.ORCID 0000-0003-1222-723X
Juan Felipe Vargas-FiqueInstitute of Developmental Biology and Neurobiology, Johannes Gutenberg-Universität Mainz, Mainz, Germany.
Miriam HenningInstitute of Developmental Biology and Neurobiology, Johannes Gutenberg-Universität Mainz, Mainz, Germany.
Burak GürInstitute of Developmental Biology and Neurobiology, Johannes Gutenberg-Universität Mainz, Mainz, Germany.ORCID 0000-0001-8221-9767
T Moritz SchladtDepartment of Molecular Sensory Systems, Center of Advanced European Studies and Research (caesar), Bonn, Germany.
Junaid AkhtarInstitute of Developmental Biology and Neurobiology, Johannes Gutenberg-Universität Mainz, Mainz, Germany.
Thomas K BergerDepartment of Molecular Sensory Systems, Center of Advanced European Studies and Research (caesar), Bonn, Germany.
Marion SiliesInstitute of Developmental Biology and Neurobiology, Johannes Gutenberg-Universität Mainz, Mainz, Germany.ORCID 0000-0003-2810-9828
Max Planck Society · DECenter of Advanced European Studies and Research · DEJohannes Gutenberg University Mainz · DEPhilipps University of Marburg · DE

Funding

Deutsche Forschungsgemeinschaft Emmy Noether SI 1991/1-1Deutsche Forschungsgemeinschaft Project C08Deutsche Forschungsgemeinschaft SFB889Deutsche Forschungsgemeinschaft SFB889, Project C08
6 · The paper itself

Abstract

Sensory systems sequentially extract increasingly complex features. ON and OFF pathways, for example, encode increases or decreases of a stimulus from a common input. This ON/OFF pathway split is thought to occur at individual synaptic connections through a sign-inverting synapse in one of the pathways. Here, we show that ON selectivity is a multisynaptic process in the

Indexed as

Visual PerceptionAnimalsDrosophilaExcitatory Amino Acid AgentsGABA AgentsInterneuronsModels, NeurologicalVisual PathwaysExcitatory Amino Acid AgentsGABA Agentsdistributed codingD. melanogasterfeature extractionGABAergic inhibitionglutamatergic inhibitionneuroscienceON selectivityvision

Identifiers

PMID31535971
PMCPMC6845231
OpenAlexW2974015364

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.