Evidence map›Paper›PMID 31535239›Full record

ArticleTechniques in coloproctology2019

Rectal advancement flap plus adipose lipofilling (RAFAL) for the treatment of rectourethral fistulas after radical prostatectomy.

M Zuin, M Ruperto, M Balduino, A Amodeo, L De Zorzi, B Roche, M Pavanello, C Sernagiotto

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in Techniques in coloproctology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

M ZuinDipartimento di Scienze Chirurgiche, Oncologiche e Gastroenterologiche, Università degli Studi di Padova, Clinica Chirurgica 1, Via Giustiniani 2, Padova, 35128, Italy. matteo.zuin@yahoo.it.
M RupertoU.O.C. Chirurgia Generale, Ospedale San Giacomo - ULSS 2, Castelfranco Veneto, Italy.
M BalduinoU.O.C. Chirurgia Generale, Ospedale San Giacomo - ULSS 2, Castelfranco Veneto, Italy.
A AmodeoIOV I.R.C.C.S, U.O.C. Urologia, Castelfranco Veneto, Italy.
L De ZorziIOV I.R.C.C.S, U.O.C. Urologia, Castelfranco Veneto, Italy.
B RocheDivision of Visceral Surgery, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland.
M PavanelloOspedale di Conegliano Veneto - ULSS 2, U.O.C. Chirurgia Generale, Conegliano, Italy.
C SernagiottoOspedale di Conegliano Veneto - ULSS 2, U.O.C. Chirurgia Generale, Conegliano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRectourethral fistula (RUF) is a rare but significant complication after radical prostatectomy. Many different approaches have been used, but none of them has become the standard of care.

methodsWe present our series of seven patients treated with a transanal rectal advancement flap plus the injection of mesenchymal stem cells, to facilitate the healing of the fistula. Mesenchymal cells were obtained by a new mechanical device known as LIPOGEMS

resultsAfter a median follow-up of 53 months (range 6-163 months), 2 out of 7 patients experienced RUF recurrence. In both cases recurrence was successfully treated by the York-Mason technique in one case and by redo RAFAL in the other. Success rate of RAFAL was 71% (5 of 7). The total success rate of primary RAFAL and redo- RAFAL was 85.7% (6 of 7). No short- or long-term complications were seen.

conclusionsIn our patient population this new procedure was safe and effective.

Indexed as

Surgical FlapsAgedHumansMaleMesenchymal Stem CellsMesenchymal Stem Cell TransplantationMiddle AgedPostoperative ComplicationsProstatectomyProstatic NeoplasmsRectal FistulaRectumTreatment OutcomeUrethral DiseasesUrinary FistulaLIPOGEMS®Mesenchymal stem cells (MSCs)Rectourethral fistulaTransanal advancement flap

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.