ReviewJournal of anesthesia2020
Medical cannabis for chronic pain: can it make a difference in pain management?
Review in Journal of anesthesia, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 44 citations in OpenAlex.
- Effects of delta-9 tetrahydrocannabinol and cannabidiol on cognitive outcomes following acute use of cannabis for chronic pain.Psychopharmacology · 2026Article
- Medical cannabis for the management of pain in chronic pancreatitis with recurrent exacerbations: a case report.Journal of cannabis research · 2025Article
- Preoperative Cannabis Use Did Not Increase Opioid Utilization After Primary Total Knee Arthroplasty in a Propensity Score-Matched Model.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2024Article
- Optogenetic Activation of Peripheral Somatosensory Neurons in Transgenic Mice as a Neuropathic Pain Model for Assessing the Therapeutic Efficacy of Analgesics.ACS pharmacology & translational science · 2024Article
- Perceptions, Attitudes, and Knowledge of Cannabis and its Use: A Qualitative Study among Herbal Heart Study Young Adult Cannabis Consumers in South Florida.Preventive medicine reports · 2024Article
- Temporal associations between use of psychoactive substances and somatic symptoms in the daily lives of people with fibromyalgia.Pain medicine (Malden, Mass.) · 2023Article
- Evaluation of the Analgesic Effect of High-Cannabidiol-Content Cannabis Extracts in Different Pain Models by Using Polymeric Micelles as Vehicles.Molecules (Basel, Switzerland) · 2023Article
- The Opioid Epidemic and Children's Living Arrangements in the United States, 2000-2018.The Annals of the American Academy of Political and Social Science · 2022Article
- Practical Considerations for the Use of Cannabis in Cancer Pain Management-What a Medical Oncologist Should Know.Journal of clinical medicine · 2022Review
- Cannabis use, pain interference, and prescription opioid receipt among persons with HIV: a target trial emulation study.AIDS care · 2022Article
- "The Two Sides of the Same Coin"-Medical Cannabis, Cannabinoids and Immunity: Pros and Cons Explained.Pharmaceutics · 2022Review
- Association of cannabis and/or opioid with quality of life and healthcare utilization in patients with chronic pain.Frontiers in pain research (Lausanne, Switzerland) · 2022Article
- Clinical Outcome Data of First Cohort of Chronic Pain Patients Treated With Cannabis-Based Sublingual Oils in the United Kingdom: Analysis From the UK Medical Cannabis Registry.Journal of clinical pharmacology · 2021Article
- Gaps in evidence for the use of medically authorized cannabis: Ontario and Alberta, Canada.Harm reduction journal · 2021Article
- Mixed methods study of the potential therapeutic benefits from medical cannabis for patients in Florida.Complementary therapies in medicine · 2021Article
- Medical cannabis in supportive cancer care: lessons from Canada.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Article
- Medical cannabis for orthopaedic patients with chronic musculoskeletal pain: does evidence support its use?Therapeutic advances in musculoskeletal disease · 2020Review
- Cannabis and pain: a scoping review.Brazilian journal of anesthesiology (Elsevier)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Globally, chronic pain is a major therapeutic challenge and affects more than 15% of the population. As patients with painful terminal diseases may face unbearable pain, there is a need for more potent analgesics. Although opioid-based therapeutic agents received attention to manage severe pain, their adverse drug effects and mortality rate associated with opioids overdose are the major concerns. Evidences from clinical trials showed therapeutic benefits of cannabis, especially delta-9-tetrahydrocannabinol and cannabinoids reduced neuropathic pain intensity in various conditions. Also, there are reports on using combination cannabinoid therapies for chronic pain management. The association of cannabis dependence and addiction has been discussed much and the reports mentioned that it can be comparatively lower than other substances such as nicotine and alcohol. More countries have decided to legalise the medicinal use of cannabis and marijuana. Healthcare professionals should keep themselves updated with the changing state of medical cannabis and its applications. The pharmacokinetics and safety of medical cannabis need to be studied by conducting clinical research. The complex and variable chemically active contents of herbal cannabis and methodological limitations in the administration of cannabis to study participants, make the clinical research difficult.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.