Evidence map›Paper›PMID 31535217›Full record

ArticleEuropean journal of applied physiology2019

Associations of physical activity, sedentary time, and cardiorespiratory fitness with heart rate variability in 6- to 9-year-old children: the PANIC study.

Aapo Veijalainen, Eero A Haapala, Juuso Väistö, Marja H Leppänen, Niina Lintu, Tuomo Tompuri, Santeri Seppälä, Ulf Ekelund, Mika P Tarvainen, Kate Westgate and 2 more

Open access · hybridAbstract read
In one paragraph

Article in European journal of applied physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Aapo VeijalainenInstitute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, PO Box 1627, 70211, Kuopio, Finland. veijalai@uef.fi.ORCID http://orcid.org/0000-0002-6838-5061
Eero A HaapalaInstitute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, PO Box 1627, 70211, Kuopio, Finland.
Juuso VäistöInstitute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, PO Box 1627, 70211, Kuopio, Finland.
Marja H LeppänenFaculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.
Niina LintuInstitute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, PO Box 1627, 70211, Kuopio, Finland.
Tuomo TompuriInstitute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, PO Box 1627, 70211, Kuopio, Finland.
Santeri SeppäläInstitute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, PO Box 1627, 70211, Kuopio, Finland.
Ulf EkelundDepartment of Sport Medicine, Norwegian School of Sport Sciences, Oslo, Norway.
Mika P TarvainenDepartment of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.
Kate WestgateMRC Epidemiology Unit, Institute of Metabolic Science, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Søren BrageMRC Epidemiology Unit, Institute of Metabolic Science, School of Clinical Medicine, University of Cambridge, Cambridge, UK.
Timo A LakkaInstitute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, PO Box 1627, 70211, Kuopio, Finland.
University of Eastern Finland · FIUniversity of Cambridge · GBFolkhälsans Forskningscentrum · FINorwegian School of Sport Sciences · NO

Funding

Medical Research Council MC_UU_12015/3NIHR Cambridge Biomedical Research Center IS-BRC-1215-20014NIHR Cambridge Biomedical Research Centre IS-BRC-1215-20014UK Medical Research Council MC_UU_12015/3
6 · The paper itself

Abstract

purposeTo study the associations of physical activity (PA), sedentary time (ST), and cardiorespiratory fitness (CRF) with heart rate variability (HRV) in children.

methodsThe participants were a population sample of 377 children aged 6-9 years (49% boys). ST, light PA (LPA), moderate PA (MPA), vigorous PA (VPA), and moderate-to-vigorous PA (MVPA), and PA energy expenditure (PAEE) were assessed using a combined heart rate and movement sensor, maximal power output per kilograms of lean body mass as a measure of CRF by maximal cycle ergometer exercise test, and HRV variables (SDNN, RMSSD, LF, and HF) using 5 min resting electrocardiography. Data were analysed by linear regression adjusted for years from peak height velocity.

resultsIn boys, ST was inversely associated (β = - 0.185 to - 0.146, p ≤ 0.049) and MVPA, VPA, PAEE, and CRF were directly associated (β = 0.147 to 0.320, p ≤ 0.048) with HRV variables. CRF was directly associated with all HRV variables and PAEE was directly associated with RMSSD after mutual adjustment for ST, PAEE, and CRF (β = 0.169 to 0.270, p ≤ 0.046). In girls, ST was inversely associated (β = - 0.382 to - 0.294, p < 0.001) and LPA, MPA, VPA, MVPA, and PAEE were directly associated with HRV variables (β = 0.144 to 0.348, p ≤ 0.049). After mutual adjustment for ST, PAEE, and CRF, only the inverse associations of ST with HRV variables remained statistically significant.

conclusionsHigher ST and lower PA and CRF were associated with poorer cardiac autonomic nervous system function in children. Lower CRF in boys and higher ST in girls were the strongest correlates of poorer cardiac autonomic function.

Indexed as

Body CompositionCardiorespiratory FitnessChildCross-Sectional StudiesEnergy MetabolismExerciseExercise TestFemaleHeart RateHumansMalePhysical FitnessSedentary BehaviorAutonomic nervous systemCardiorespiratory fitnessChildrenPhysical activity

Identifiers

PMID31535217
PMCPMC6858383
OpenAlexW2973056530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.