Evidence map›Paper›PMID 31535190›Full record

ReviewDer Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft2019

[Toxicity of heavy liquids].

Kai Januschowski, Peter Szurman, Koen Willekens, Michael J Bojdys, Karl Boden

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. OVD-assisted press injection in gasless surgery for sectorial inverted internal limiting membrane flap stabilization.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kai JanuschowskiAugenklinik Sulzbach, Knappschaftsklinikum Saar GmbH, An der Klinik 10, 66280, Sulzbach/Saar, Deutschland. kai.januschowski@kksaar.de.
Peter SzurmanAugenklinik Sulzbach, Knappschaftsklinikum Saar GmbH, An der Klinik 10, 66280, Sulzbach/Saar, Deutschland.
Koen WillekensDepartment für Augenheilkunde, Universitätsaugenklinikum Löwen, Herestraat 49, 3000, Löwen, Belgien.
Michael J BojdysDepartment für Chemie, Humboldt-Universität zu Berlin, Brook-Taylor-Str. 2, 12489, Berlin, Deutschland.
Karl BodenAugenklinik Sulzbach, Knappschaftsklinikum Saar GmbH, An der Klinik 10, 66280, Sulzbach/Saar, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute toxicity of perfluorocarbon liquids (PFCL) is a relevant problem in retinal surgery due to impurities in the medicinal product.

objectiveThis article gives an overview of the current problems, possible explanations, interactions with other medicinal products and approaches to improved patient safety.

resultsToxicity is caused by impurities in the raw material but can also be caused by interactions with other medicinal products or drugs. The current test procedures do not ideally represent the ophthalmological application but there are promising activities to set the course for the future.

conclusionThe use of PFCL in retinal surgery is generally considered safe. Users should pay attention to the quality of medicinal products.

Indexed as

FluorocarbonsHumansOphthalmologic Surgical ProceduresRetinaFluorocarbonsImpurityMedicinal productsPatient safetyPerfluorocarbon liquidsRetinal surgery

Identifiers

PMID31535190

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.