Evidence map›Paper›PMID 31535089›Full record

ArticleAnnals of pancreatic cancer2019

Insights into the biology and treatment strategies of pancreatic neuroendocrine tumors.

Jessica L Buicko, Brendan M Finnerty, Tiantian Zhang, Bu Jung Kim, Thomas J Fahey, Yi-Chieh Nancy Du

Open access · diamondAbstract read
In one paragraph

Article in Annals of pancreatic cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  8. "Annals of pancreatic cancer · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jessica L BuickoDepartment of Surgery, Weill Cornell Medicine, New York, NY 10065, USA.
Brendan M FinnertyDepartment of Surgery, Weill Cornell Medicine, New York, NY 10065, USA.
Tiantian ZhangDepartment of Pathology & Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
Bu Jung KimDepartment of Pathology & Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
Thomas J FaheyDepartment of Surgery, Weill Cornell Medicine, New York, NY 10065, USA.
Yi-Chieh Nancy DuDepartment of Pathology & Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
Weill Cornell Medicine · USCornell University · US

Funding

Beyond apoptosis, Bcl-xL in tumor metastasisR01CA204916 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI DU, YI-CHIEH NANCY · 2017 to 2021
$2.0M
NCI NIH HHS R01 CA204916
6 · The paper itself

Abstract

Pancreatic neuroendocrine tumors (PNETs) are the second most common primary pancreatic neoplasms after pancreatic ductal adenocarcinoma. PNETs present with widely various clinical manifestation and unfavorable survival rate. The recent advances in next generation sequencing have significantly increased our understanding of the molecular landscape of PNETs and help guide the development of targeted therapies. This review intends to outline a holistic picture of the tumors by discussing current understanding of clinical presentations, up-to-date treatment strategies, novel mouse models, and molecular biology of PNETs. Furthermore, we will provide insight into the future development of more effective targeted therapies that are necessary to manage PNETs.

Indexed as

molecular characterizationmouse modelsPancreatic neuroendocrine tumors (PNETs)therapies

Identifiers

PMID31535089
PMCPMC6750261
OpenAlexW2949398636

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.