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Efficacy of
Article in OTO open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 3 citations in OpenAlex.
- Risk factors and distribution pattern of lateral lymph node recurrence after central neck dissection for cN1a papillary thyroid carcinoma.BMC surgery · 2024Article
- Radiomics Profiling Identifies the Value of CT Features for the Preoperative Evaluation of Lymph Node Metastasis in Papillary Thyroid Carcinoma.Diagnostics (Basel, Switzerland) · 2022Article
- An Ultrasound Radiomics Nomogram for Preoperative Prediction of Central Neck Lymph Node Metastasis in Papillary Thyroid Carcinoma.Frontiers in oncology · 2020Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the efficacy of preoperative STUDY
designCase series with chart review.
settingUniversity tertiary care facility. SUBJECTS AND
methodsWe retrospectively compared the pathologic results for 409 cervical LN levels in 140 patients who underwent thyroidectomy and central neck dissection with/without lateral neck dissection with the findings of preoperative PET/CT, ultrasonography (US), and CT. We judged LN metastasis in PET/CT using the maximum standardized uptake value (SUVmax) at the optimal cutoff value in receiver operating characteristic curves and compared the sensitivity, specificity, and diagnostic accuracy of the 3 imaging tools.
resultsAt all neck levels (central and lateral compartments), PET/CT had a sensitivity of 57.5%, specificity of 68.6%, and diagnostic accuracy of 63.6% when the cutoff value of SUVmax was 1.125. The corresponding values were 59.1%, 90.6%, and 76.3%, respectively, for US and 53.8%, 91.9%, and 74.6% for CT. In the central compartment (level VI), sensitivity, specificity, and diagnostic accuracy were 48.9%, 67.4%, and 59.9% for PET/CT (cutoff SUVmax 1.125); 47.8%, 96.3%, and 76.7% for US; and 41.3%, 97.0%, and 74.4% for CT, respectively. In the lateral compartment (levels II-V), the corresponding values of sensitivity, specificity, and diagnostic accuracy were 70.2%, 69.3%, and 69.8% for PET/CT (cutoff SUVmax 1.055); 70.2%, 81.8%, and 75.8% for US; and 65.9%, 84.1%, and 74.7% for CT.
conclusionPET/CT is less effective as a preoperative diagnostic tool for detecting cervical lymph node metastasis in PTC than US or CT.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.