Evidence map›Paper›PMID 31534620›Full record

ReviewOxidative medicine and cellular longevity2019

Medicinal Plants from Brazilian Cerrado: Antioxidant and Anticancer Potential and Protection against Chemotherapy Toxicity.

José Tarcísio de Giffoni de Carvalho, Débora da Silva Baldivia, Daniel Ferreira Leite, Laura Costa Alves de Araújo, Priscilla Pereira de Toledo Espindola, Katia Avila Antunes, Paola Santos Rocha, Kely de Picoli Souza, Edson Lucas Dos Santos

Open access · hybridAbstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
7.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 52 citations in OpenAlex.

  1. Phytochemical Profiling and Antioxidant Activity ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Propolis: A Natural Substance with Multifaceted Properties and Activities.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Chemical Composition, Antioxidant, and Cytotoxic Effects ofPharmaceuticals (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

José Tarcísio de Giffoni de CarvalhoResearch Group on Biotechnology and Bioprospecting Applied to Metabolism, Federal University of Grande Dourados, Dourados, Brazil.ORCID https://orcid.org/0000-0001-7897-8218
Débora da Silva BaldiviaResearch Group on Biotechnology and Bioprospecting Applied to Metabolism, Federal University of Grande Dourados, Dourados, Brazil.
Daniel Ferreira LeiteResearch Group on Biotechnology and Bioprospecting Applied to Metabolism, Federal University of Grande Dourados, Dourados, Brazil.
Laura Costa Alves de AraújoResearch Group on Biotechnology and Bioprospecting Applied to Metabolism, Federal University of Grande Dourados, Dourados, Brazil.
Priscilla Pereira de Toledo EspindolaResearch Group on Biotechnology and Bioprospecting Applied to Metabolism, Federal University of Grande Dourados, Dourados, Brazil.
Katia Avila AntunesResearch Group on Biotechnology and Bioprospecting Applied to Metabolism, Federal University of Grande Dourados, Dourados, Brazil.ORCID https://orcid.org/0000-0002-0451-5189
Paola Santos RochaResearch Group on Biotechnology and Bioprospecting Applied to Metabolism, Federal University of Grande Dourados, Dourados, Brazil.ORCID https://orcid.org/0000-0003-1019-1202
Kely de Picoli SouzaResearch Group on Biotechnology and Bioprospecting Applied to Metabolism, Federal University of Grande Dourados, Dourados, Brazil.ORCID https://orcid.org/0000-0001-5764-2125
Edson Lucas Dos SantosResearch Group on Biotechnology and Bioprospecting Applied to Metabolism, Federal University of Grande Dourados, Dourados, Brazil.ORCID https://orcid.org/0000-0002-6557-7914
Universidade Federal da Grande Dourados · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of natural antioxidants in cancer therapy has increased: first, due to the potential of natural antioxidants to kill tumour cells and second, because of their capacity to protect healthy cells from the damage caused by chemotherapy. This review article discusses the antioxidant properties of extracts obtained from medicinal plants from the Brazilian Cerrado and the cell death profile induced by each of these extracts in malignant cells. Next, we describe the capacity of other medicinal plants from the Cerrado to protect against chemotherapy-induced cell toxicity. Finally, we focus on recent insights into the cell death profile induced by extracts from Cerrado plants and perspectives for future therapeutic approaches.

Indexed as

Antineoplastic AgentsAntioxidantsBrazilHumansPlant ExtractsPlants, MedicinalProtective AgentsAntineoplastic AgentsAntioxidantsPlant ExtractsProtective Agents

Identifiers

PMID31534620
PMCPMC6732650
OpenAlexW2969607408

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.