Evidence map›Paper›PMID 31534606›Full record

ArticleThe Neurohospitalist2019

Recrudescence of Old Stroke Deficits Among Transient Neurological Attacks.

Adalia H Jun-O'connell, Nils Henninger, Majaz Moonis, Brian Silver, Carolina Ionete, Richard P Goddeau

Open access · greenAbstract read
In one paragraph

Article in The Neurohospitalist, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. A 58-year-old patient with right-sided weakness and a history of stroke.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
    Article
  2. Review
  3. Observational
  4. Article
  5. Postoperative Neurologic Deficits in a Veteran With Recent COVID-19.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2021
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Adalia H Jun-O'connellDepartment of Neurology, University of Massachusetts Medical School, Worcester, MA, USA.ORCID https://orcid.org/0000-0003-0667-2951
Nils HenningerDepartment of Neurology, University of Massachusetts Medical School, Worcester, MA, USA.
Majaz MoonisDepartment of Neurology, University of Massachusetts Medical School, Worcester, MA, USA.
Brian SilverDepartment of Neurology, University of Massachusetts Medical School, Worcester, MA, USA.
Carolina IoneteDepartment of Neurology, University of Massachusetts Medical School, Worcester, MA, USA.
Richard P GoddeauDepartment of Neurology, University of Massachusetts Medical School, Worcester, MA, USA.
University of Massachusetts Chan Medical School · US

Funding

Inhibiting axon degeneration in a mouse model of acute brain injury through deletion of Sarm1K08NS091499 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI HENNINGER, NILS · 2016 to 2020
$919k
NINDS NIH HHS K08 NS091499
6 · The paper itself

Abstract

backgroundRecrudescence of old stroke deficits (ROSD) is a reported cause of transient neurological symptoms, but it is not well characterized.

objectiveWe sought to determine the prevalence, potential triggers, and clinical outcome of ROSD in a cohort of patients presenting with acute transient neurological attack (TNA) and absent acute pathology on brain imaging.

methodsWe retrospectively analyzed 340 consecutive patients who presented with TNA and no acute pathology on brain imaging that were included in an institutional stroke registry between February 2013 and April 2015. The presumed TNA cause was categorized as transient ischemic attack (TIA), ROSD, and other cause. Baseline characteristics, triggers, cardiovascular complications within 90 days, and death were recorded.

resultsThe prevalence of ROSD in the studied cohort was 10% (34/340). Infectious stressors and acute metabolite derangements were more common in ROSD compared to TIA (

conclusionROSD is common and distinct from TIA and is associated with a triggering physiologic reaction leading to transient reemergence of prior neurologic deficits. Further study of the mechanism of this phenomenon is needed to help better identify these patients.

Indexed as

diagnosisexacerbation of focal neurological deficitslocus minoris resistantiaepoststroke recrudescencereactivation of prior deficitsstroketransient neurological symptoms

Identifiers

PMID31534606
PMCPMC6739667
OpenAlexW2916471211

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.