ReviewWorld journal of emergency medicine2019
The utility of point-of-care ultrasound in the assessment of volume status in acute and critically ill patients.
Review in World journal of emergency medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Critical Care Ultrasonography for Volume Management: A Systematic Review, Meta-Analysis, and Trial Sequential Analysis of Randomized Trials.Critical care explorations · 2025Pooled it
- Cellular and Molecular Mechanisms of Hemorrhagic Shock: Biological Rationale for Individualized Fluid Resuscitation Strategies and Multimodal Monitoring.Biomedicines · 2026Review
- The fluid paradox: dissociation between clinical and ultrasound parameters of fluid overload - results of the INCIVEX exploratory study.Anaesthesiology intensive therapy · 2026Observational
- Point-of-care-ultrasound measurements of cardiovascular indices across awake, sedated, anesthetized, and recovered states in dogs.Frontiers in veterinary science · 2026Article
- Assessment of Fluid Responsiveness via Central Venous Ultrasound Measurement: A Network Meta-Analysis.Journal of clinical medicine · 2025Review
- Construction of a right ventricular function assessment model in patients undergoing invasive mechanical ventilation based on VExUS grading and the classification and regression tree algorithm.Frontiers in cardiovascular medicine · 2025Article
- Article
- Inferior vena cava ultrasound and other techniques for assessment of intravascular and extravascular volume: an update.Clinical kidney journal · 2023Review
- Processing Ultrasound Scans of the Inferior Vena Cava: Techniques and Applications.Bioengineering (Basel, Switzerland) · 2023Review
- Intra-and inter-observer variability of point of care ultrasound measurements to evaluate hemodynamic parameters in healthy volunteers.The ultrasound journal · 2023Article
- Norepinephrine May Exacerbate Septic Acute Kidney Injury: A Narrative Review.Journal of clinical medicine · 2023Review
- Pre-anesthesia ultrasound monitoring of subclavian vein diameter changes induced by modified passive leg raising can predict the occurrence of hypotension after general anesthesia: a prospective observational study.BMC anesthesiology · 2023Observational
- Classification of clinically relevant intravascular volume status using point of care ultrasound and machine learning.Journal of medical imaging (Bellingham, Wash.) · 2022Article
- Assessment of prescribed vs. achieved fluid balance during continuous renal replacement therapy and mortality outcome.PloS one · 2022Article
- Diagnostic Accuracy of Ultrasonographic Respiratory Variation in the Inferior Vena Cava, Subclavian Vein, Internal Jugular Vein, and Femoral Vein Diameter to Predict Fluid Responsiveness: A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2021Article
- Effectiveness of an educational program on improving healthcare providers' knowledge of acute stroke: A randomized block design study.World journal of emergency medicine · 2021Article
- Point-of-care ultrasound to evaluate volume status in severe hyponatremia.BMJ case reports · 2020Article
- Retrospective analysis of eFAST ultrasounds performed on trauma activations at an academic level-1 trauma center.World journal of emergency medicine · 2020Article
- Effect of neutrophil CD64 for diagnosing sepsis in emergency department.World journal of emergency medicine · 2020Article
- The diagnostic accuracy of preoperative perfusion index as a predictor of postspinal anesthesia hypotension in parturients undergoing cesarean delivery: A prospective non-blinded observational study.Saudi journal of anaesthesiaArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVolume resuscitation has only been demonstrated to be effective in approximately fifty percent of patients. The remaining patients do not respond to volume resuscitation and may even develop adverse outcomes (such as acute pulmonary edema necessitating endotracheal intubation). We believe that point-of-care ultrasound is an excellent modality by which to adequately predict which patients may benefit from volume resuscitation. DATA RESOURCES: We performed a search using PubMed, Scopus, and MEDLINE. The following search terms were used: fluid responsiveness, ultrasound, non-invasive, hemodynamic, fluid challenge, and passive leg raise. Preference was given to clinical trials and review articles that were most relevant to the topic of assessing a patient's cardiovascular ability to respond to intravenous fluid administration using ultrasound.
resultsPoint-of-care ultrasound can be easily employed to measure the diameter and collapsibility of various large vessels including the inferior vena cava, common carotid artery, subclavian vein, internal jugular vein, and femoral vein. Such parameters are closely related to dynamic measures of fluid responsiveness and can be used by providers to help guide fluid resuscitation in critically ill patients.
conclusionUltrasound in combination with passive leg raise is a non-invasive, cost- and time-effective modality that can be employed to assess volume status and response to fluid resuscitation. Traditionally sonographic studies have focused on the evaluation of large veins such as the inferior vena cava, and internal jugular vein. A number of recently published studies also demonstrate the usefulness of evaluating large arteries to predict volume status.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.