Evidence map›Paper›PMID 31534544›Full record

ArticleTheranostics2019

DNA methylation-regulated QPCT promotes sunitinib resistance by increasing HRAS stability in renal cell carcinoma.

Tangliang Zhao, Yi Bao, Xinxin Gan, Jie Wang, Qiong Chen, Zhihui Dai, Bing Liu, Anbang Wang, Shuhan Sun, Fu Yang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 52 citations in OpenAlex.

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  18. Molecular mechanisms of resistance to tyrosine kinase inhibitor in clear cell renal cell carcinoma.International journal of urology : official journal of the Japanese Urological Association · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Tangliang ZhaoDepartment of Urology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China.
Yi BaoDepartment of Urology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China.
Xinxin GanDepartment of Urology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China.
Jie WangDepartment of Urology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China.
Qiong ChenDepartment of Urology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China.
Zhihui DaiDepartment of Medical Genetics, Second Military Medical University, Shanghai 200433, China.
Bing LiuDepartment of Urology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China.
Anbang WangDepartment of Urology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China.
Shuhan SunDepartment of Medical Genetics, Second Military Medical University, Shanghai 200433, China.
Fu YangDepartment of Medical Genetics, Second Military Medical University, Shanghai 200433, China.
Linhui WangDepartment of Urology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China.
Second Military Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug Resistance, NeoplasmGene Expression Regulation, NeoplasticMAP Kinase Signaling SystemAnimalsCarcinoma, Renal CellCell Line, TumorDNA MethylationHumansImmunohistochemistryKidney NeoplasmsMaleMiceMice, Inbred BALB CPromoter Regions, GeneticProteomeProto-Oncogene Proteins p21(ras)HRAS protein, humanProteomeProto-Oncogene Proteins p21(ras)SunitinibDNA methylationGlutaminyl peptide cyclotransferaseHRASRenal cell carcinomaSunitinib

Identifiers

PMID31534544
PMCPMC6735520
OpenAlexW2972985548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.