Evidence map›Paper›PMID 31534529›Full record

ArticleTheranostics2019

TRAIL acts synergistically with iron oxide nanocluster-mediated magneto- and photothermia.

Hanene Belkahla, Eva Mazarío, Anouchka Plan Sangnier, John S Lomas, Tijani Gharbi, Souad Ammar, Olivier Micheau, Claire Wilhelm, Miryana Hémadi

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Hanene BelkahlaUniversité de Paris, ITODYS, CNRS-UMR 7086, 15 rue J.-A. de Baïf, F-75013 Paris, France.
Eva MazaríoUniversité de Paris, ITODYS, CNRS-UMR 7086, 15 rue J.-A. de Baïf, F-75013 Paris, France.
Anouchka Plan SangnierLaboratoire Matières et Systèmes Complexes, Université de Paris, CNRS-UMR 7057, 10 rue Alice Domon et Léonie Duquet, 75205 Paris Cedex 13, France.
John S LomasUniversité de Paris, ITODYS, CNRS-UMR 7086, 15 rue J.-A. de Baïf, F-75013 Paris, France.
Tijani GharbiNanomedicine, Imagery and Therapeutics, EA 4662, Université de Bourgogne Franche-Comté, UFR Sciences & Techniques, 16 Route de Gray, 25030 Besançon Cedex, France.
Souad AmmarUniversité de Paris, ITODYS, CNRS-UMR 7086, 15 rue J.-A. de Baïf, F-75013 Paris, France.
Olivier MicheauLipides nutrition cancer, INSERM-UMR 1231, Université de Bourgogne Franche-Comté, UFR Science de Santé, 7 Bd Jeanne d'Arc, 21000 Dijon, France.
Claire WilhelmLaboratoire Matières et Systèmes Complexes, Université de Paris, CNRS-UMR 7057, 10 rue Alice Domon et Léonie Duquet, 75205 Paris Cedex 13, France.
Miryana HémadiUniversité de Paris, ITODYS, CNRS-UMR 7086, 15 rue J.-A. de Baïf, F-75013 Paris, France.
Université Paris Cité · FRCentre National de la Recherche Scientifique · FRInterfaces Traitements Organisation et Dynamique des Systèmes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Targeting TRAIL (Tumor necrosis factor (TNF)-Related Apoptosis-Inducing Ligand) receptors for cancer therapy remains challenging due to tumor cell resistance and poor preparations of TRAIL or its derivatives. Herein, to optimize its therapeutic use, TRAIL was grafted onto iron oxide nanoclusters (NCs) with the aim of increasing its pro-apoptotic potential through nanoparticle-mediated magnetic hyperthermia (MHT) or photothermia (PT).

Indexed as

ApoptosisCell DeathCell Line, TumorCell SurvivalFerric CompoundsFlow CytometryHumansHyperthermia, InducedMicroscopy, Electron, TransmissionTNF-Related Apoptosis-Inducing LigandTumor Necrosis Factor-alphaFerric Compoundsferric oxideTNF-Related Apoptosis-Inducing LigandTumor Necrosis Factor-alphaapoptosisiron oxide nanoclustersmagnetic hyperthermiaphotothermal therapyTRAIL

Identifiers

PMID31534529
PMCPMC6735372
OpenAlexW2973149592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.