Evidence map›Paper›PMID 31534449›Full record

ArticleNeural plasticity2019

Novelty and Novel Objects Increase c-Fos Immunoreactivity in Mossy Cells in the Mouse Dentate Gyrus.

Hannah L Bernstein, Yi-Ling Lu, Justin J Botterill, Helen E Scharfman

Open access · goldAbstract read
In one paragraph

Article in Neural plasticity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
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  6. Review
  7. Intrinsic and Synaptic Contributions to Repetitive Spiking in Dentate Granule Cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
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  11. Review
  12. Article
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  18. Article
  19. Bidirectional Regulation of Cognitive and Anxiety-like Behaviors by Dentate Gyrus Mossy Cells in Male and Female Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hannah L BernsteinThe Nathan S. Kline Institute for Psychiatric Research, Center for Dementia Research, 140 Old Orangeburg Rd., Orangeburg, NY 10962, USA.ORCID 0000-0002-6512-1378
Yi-Ling LuThe Nathan S. Kline Institute for Psychiatric Research, Center for Dementia Research, 140 Old Orangeburg Rd., Orangeburg, NY 10962, USA.ORCID 0000-0002-7545-8011
Justin J BotterillThe Nathan S. Kline Institute for Psychiatric Research, Center for Dementia Research, 140 Old Orangeburg Rd., Orangeburg, NY 10962, USA.ORCID 0000-0002-3141-2281
Helen E ScharfmanThe Nathan S. Kline Institute for Psychiatric Research, Center for Dementia Research, 140 Old Orangeburg Rd., Orangeburg, NY 10962, USA.ORCID 0000-0003-4006-3383
Nathan Kline Institute for Psychiatric Research · US

Funding

MEDICAL SCIENTIST TRAININGT32GM007308 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI PHILIPS, MARK REID · 1985 to 2019
$23.2M
Hilar mossy cells and dentate gyrus functionR01MH109305 · NIMH · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · PI SCHARFMAN, HELEN E · 2016 to 2020
$2.0M
Probing the function of hilar mossy cells in hippocampal circuits and dentate gyrus-dependent behaviorsF30MH110165 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BERNSTEIN, HANNAH LAURA · 2016 to 2018
$104k
NIGMS NIH HHS T32 GM007308NIMH NIH HHS F30 MH110165NIMH NIH HHS R01 MH109305
6 · The paper itself

Abstract

The dentate gyrus (DG) and its primary cell type, the granule cell (GC), are thought to be critical to many cognitive functions. A major neuronal subtype of the DG is the hilar mossy cell (MC). MCs have been considered to play an important role in cognition, but

Indexed as

AnimalsDentate GyrusExploratory BehaviorMaleMiceMossy Fibers, HippocampalProto-Oncogene Proteins c-fosProto-Oncogene Proteins c-fos

Identifiers

PMID31534449
PMCPMC6732597
OpenAlexW2971113538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.