Evidence map›Paper›PMID 31534359›Full record

ArticleJournal of pain research2019

Working towards a consensus on the oncological approach of breakthrough pain: a Delphi survey of Spanish experts.

Carlos Camps Herrero, Antonio Antón Torres, Juan Jesús Cruz-Hernández, Alfredo Carrato, Manuel Constenla, Eduardo Díaz-Rubio, Margarita Feyjoo Saus, Jesus Garcia-Foncillas, Pere Gascón, Vicente Guillem

Open access · goldAbstract read
In one paragraph

Article in Journal of pain research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 10 institutions in 1 country.

Carlos Camps HerreroJefe de Servicio de Oncología Médica, Consorcio Hospital General Universitario, Valencia, Spain.
Antonio Antón TorresJefe del Servicio de Oncología Médica, Hospital Universitario Miguel Servet, Zaragoza, Spain.
Juan Jesús Cruz-HernándezJefe del Servicio de Oncología Médica, Hospital Universitario De Salamanca-IBSAL, Salamanca, Spain.
Alfredo CarratoJefe del Servicio de Oncología Médica, Hospital Universitario Ramón y Cajal, Madrid, Spain.
Manuel ConstenlaJefe de Servicio de Oncología, Complejo Hospitalario Universitario de Pontevedra, Pontevedra, Spain.
Eduardo Díaz-RubioJefe del Servicio de Oncología Médica, Hospital Universitario Clínico San Carlos, Madrid, Spain.
Margarita Feyjoo SausJefe del Servicio de Oncología Médica, Hospital La Moraleja, Madrid, Spain.
Jesus Garcia-FoncillasJefe de Servicio de Oncología Médica, Hospital Universitario "Fundación Jiménez Díaz", Madrid, Spain.
Pere GascónJefe del Servicio de Oncología Médica, Hospital Clínic, IDIBAPS, Universidad de Barcelona, Barcelona, Spain.
Vicente GuillemJefe del Servicio de Oncología Médica, Instituto Valenciano de Oncología, Valencia, Spain.
Complejo Hospitalario de Pontevedra · ESFundación Instituto Valenciano de Oncología · ESHospital Clínico San Carlos · ESHospital General de La Rioja · ESHospital General Universitario De Valencia · ESHospital Universitario Fundación Jiménez Díaz · ESHospital Universitario Miguel Servet · ESHospital Universitario Ramón y Cajal · ESInstituto de Investigación Biomédica de Salamanca · ESUniversitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere is a lack of standards for the diagnosis, assessment and management of breakthrough cancer pain (BTcP). La Fundación ECO (the Foundation for Excellence and Quality in Oncology) commissioned a study to establish a consensus and lay the foundations for the appropriate management of BTcP in oncology patients. PATIENTS AND

methodsA modified Delphi survey comprising two rounds was used to gather and analyze data, which was conducted over the Internet. Each statement that reached a consensus with the respondents was defined as a median consensus score (MED) of ≥7, and agreement among panelists as an interquartile range (IQR) of ≤3.

resultsIn total, 69 medical oncologists responded, with a broad consensus that BTcP implied exacerbations of high-intensity pain, as opposed to moderate pain. Furthermore, they concurred that appropriate diagnostic equipment is needed, and that rapid-onset fentanyl formulations should be the preferred treatment for BTcP management. The panelists agreed that a lack of appropriate information and training to attend to patients, as well as limited patient visitation rights, were barriers to effective BTcP management. Regarding gaps in detected knowledge, the panelists were unsure of the measures necessary to assess the burden of the disease on the patient's quality of life and associated medication costs. Alongside this, there was a lack of awareness of the technical specifics of the different formulations of rapid-onset fentanyl.

conclusionThese results represent the current status of BTcP management. They may inform recommendations and provide a framework for future research.

Indexed as

breakthrough painfentanylmedical oncologypain managementrapid-onset opioids

Identifiers

PMID31534359
PMCPMC6681159
OpenAlexW2965437454

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.