Evidence map›Paper›PMID 31534265›Full record

ArticleAmerican sociological review2018

Education, Smoking, and Cohort Change: Forwarding a Multidimensional Theory of the Environmental Moderation of Genetic Effects.

Robbee Wedow, Meghan Zacher, Brooke M Huibregtse, Kathleen Mullan Harris, Benjamin W Domingue, Jason D Boardman

Abstract read
In one paragraph

Article in American sociological review, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  10. Exploring the Fetal Origins Hypothesis Using Genetic Data.Social forces; a scientific medium of social study and interpretation · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Robbee WedowDepartment of Sociology, University of Colorado, Boulder, Colorado.
Meghan ZacherSocial Science Genetic Association Consortium (SSGAC).
Brooke M HuibregtseInstitute for Behavioral Genetics, University of Colorado, Boulder, Colorado.
Kathleen Mullan HarrisCarolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Benjamin W DomingueHealth and Society Program and Population Program, Institute of Behavioral Science, University of Colorado, Boulder, Colorado.
Jason D BoardmanDepartment of Sociology, University of Colorado, Boulder, Colorado.

Funding

Wave IV Data CollectionP01HD031921 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRIS, KATHLEEN MULLAN · 1994 to 2020
$86.1M
Research Training-Genetics of Substance AbuseT32DA017637 · NIDA · UNIVERSITY OF COLORADO AT BOULDER · PI STITZEL, JERRY A · 2004 to 2023
$5.3M
Add Health: A Genotype and Phenotype Resource for the Global Scientific CommunityR01HD073342 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRIS, KATHLEEN MULLAN · 2012 to 2016
$3.6M
Social Demographic Moderation of Genome Wide Associations for Body Mass IndexR01HD060726 · NICHD · UNIVERSITY OF COLORADO · PI BOARDMAN, JASON D, MCQUEEN, MATTHEW B · 2010 to 2014
$2.7M
Genetic Risk, Pathways to Adulthood, and Health InequalitiesR01HD061622 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SHANAHAN, MICHAEL J · 2010 to 2014
$2.0M
The University of Colorado Population CenterR24HD066613 · NICHD · UNIVERSITY OF COLORADO · PI PAMPEL, FRED C · 2010 to 2014
$1.9M
University of Colorado Interdisciplinary Training in Demography and GeneticsT32AG052371 · NIA · UNIVERSITY OF COLORADO · PI BOARDMAN, JASON D · 2017 to 2020
$681k
THE SOCIAL DETERMINANTS OF GENETIC EXPRESSION: A LIFE-COURSE PERSPECTIVEK01HD050336 · NICHD · UNIVERSITY OF COLORADO AT BOULDER · PI BOARDMAN, JASON D · 2005 to 2009
$602k
NIA NIH HHS T32 AG052371NICHD NIH HHS K01 HD050336NICHD NIH HHS P01 HD031921NICHD NIH HHS R01 HD060726NICHD NIH HHS R01 HD061622NICHD NIH HHS R01 HD073342NICHD NIH HHS R24 HD066613NIDA NIH HHS T32 DA017637
6 · The paper itself

Abstract

We introduce a genetic correlation by environment interaction model [(rG)xE] which allows for social environmental moderation of the genetic relationship between two traits. To empirically demonstrate the significance of the (rG)xE perspective, we use genome wide information from respondents of the Health and Retirement Study (HRS; n = 8,181; birth years 1920-1959) and the National Longitudinal Study of Adolescent to Adult Health (Add Health; n = 4,347; birth years 1974-1983) to examine whether the genetic correlation (rG) between education and smoking has increased over historical time. Genetic correlation estimates (rG

Indexed as

educationgenetic correlationhistorical timepleiotropysmoking

Identifiers

PMID31534265
PMCPMC6750804

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.