Evidence map›Paper›PMID 31534124›Full record

ArticleNature communications2019

Lung endothelial cell antigen cross-presentation to CD8

Carla Claser, Samantha Yee Teng Nguee, Akhila Balachander, Shanshan Wu Howland, Etienne Becht, Bavani Gunasegaran, Siddesh V Hartimath, Audrey W Q Lee, Jacqueline Theng Theng Ho, Chee Bing Ong and 4 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
9.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 78 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Immunity beyond borders: non-lethalFrontiers in immunology · 2026
    Article
  7. Article
  8. Malaria: past, present, and future.Signal transduction and targeted therapy · 2025
    Review
  9. Cell Population-resolved Multiomics Atlas of the Developing Lung.American journal of respiratory cell and molecular biology · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. CD8Frontiers in cellular and infection microbiology · 2025
    Article
  16. Review
  17. Lung Damage Induced byACS infectious diseases · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Carla ClaserSingapore Immunology Network (SIgN), A*STAR, 8A Biomedical Grove, Level 3 & 4 Immunos Building, Singapore, 138648, Singapore. carla_claser@immunol.a-star.edu.sg.ORCID http://orcid.org/0000-0002-5395-9632
Samantha Yee Teng NgueeSingapore Immunology Network (SIgN), A*STAR, 8A Biomedical Grove, Level 3 & 4 Immunos Building, Singapore, 138648, Singapore.
Akhila BalachanderSingapore Immunology Network (SIgN), A*STAR, 8A Biomedical Grove, Level 3 & 4 Immunos Building, Singapore, 138648, Singapore.ORCID http://orcid.org/0000-0002-2168-0063
Shanshan Wu HowlandSingapore Immunology Network (SIgN), A*STAR, 8A Biomedical Grove, Level 3 & 4 Immunos Building, Singapore, 138648, Singapore.ORCID http://orcid.org/0000-0003-4794-1564
Etienne BechtSingapore Immunology Network (SIgN), A*STAR, 8A Biomedical Grove, Level 3 & 4 Immunos Building, Singapore, 138648, Singapore.
Bavani GunasegaranSingapore Immunology Network (SIgN), A*STAR, 8A Biomedical Grove, Level 3 & 4 Immunos Building, Singapore, 138648, Singapore.ORCID http://orcid.org/0000-0002-4783-8404
Siddesh V HartimathIsotopic Molecular Imaging Laboratory, Singapore Bioimaging Consortium (SBIC), A*STAR, 11 Biopolis Way, #02-02 Helios, Singapore, 138667, Singapore.ORCID http://orcid.org/0000-0002-8248-0866
Audrey W Q LeeSingapore Immunology Network (SIgN), A*STAR, 8A Biomedical Grove, Level 3 & 4 Immunos Building, Singapore, 138648, Singapore.ORCID http://orcid.org/0000-0002-7395-5225
Jacqueline Theng Theng HoSingapore Immunology Network (SIgN), A*STAR, 8A Biomedical Grove, Level 3 & 4 Immunos Building, Singapore, 138648, Singapore.
Chee Bing OngHistolopathology/Advanced Molecular Pathology Lab, Institute of Molecular and Cell Biology (IMCB), A*STAR, 61 Biopolis Drive, Level 6 Proteos Building, Singapore, 138673, Singapore.ORCID http://orcid.org/0000-0002-0521-1646
Evan W NewellSingapore Immunology Network (SIgN), A*STAR, 8A Biomedical Grove, Level 3 & 4 Immunos Building, Singapore, 138648, Singapore.
Julian GoggiIsotopic Molecular Imaging Laboratory, Singapore Bioimaging Consortium (SBIC), A*STAR, 11 Biopolis Way, #02-02 Helios, Singapore, 138667, Singapore.ORCID http://orcid.org/0000-0002-3021-3184
Lai Guan NgSingapore Immunology Network (SIgN), A*STAR, 8A Biomedical Grove, Level 3 & 4 Immunos Building, Singapore, 138648, Singapore.ORCID http://orcid.org/0000-0003-1905-3586
Laurent ReniaSingapore Immunology Network (SIgN), A*STAR, 8A Biomedical Grove, Level 3 & 4 Immunos Building, Singapore, 138648, Singapore. renia_laurent@immunol.a-star.edu.sg.ORCID http://orcid.org/0000-0003-0349-1557
Agency for Science, Technology and Research · SGNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria-associated acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) are life-threatening manifestations of severe malaria infections. The pathogenic mechanisms that lead to respiratory complications, such as vascular leakage, remain unclear. Here, we confirm that depleting CD8

Indexed as

Acute Lung InjuryAnimalsCD8-Positive T-LymphocytesCross-PrimingDisease Models, AnimalEndothelial CellsFemaleInterferon-gammaLungMalariaMaleMiceMice, Inbred C57BLMice, KnockoutPlasmodium bergheiPulmonary EdemaIFNG protein, mouseInterferon-gamma

Identifiers

PMID31534124
PMCPMC6751193
OpenAlexW2973912049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.