ArticleTranslational psychiatry2019
Repetitive negative thinking in daily life and functional connectivity among default mode, fronto-parietal, and salience networks.
Article in Translational psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 2 of them syntheses that pooled it.
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Who cites it
53 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Neuroscience meets behavior: A systematic literature review on magnetic resonance imaging of the brain combined with real-world digital phenotyping.Human brain mapping · 2024Pooled it
- Default Mode Network Modulation by Psychedelics: A Systematic Review.The international journal of neuropsychopharmacology · 2023Pooled it
- Ketamine's impact on rumination-related brain dynamics: insights from a randomized controlled fMRI trial.Translational psychiatry · 2026Trial
- Increased global integration in the brain after psilocybin therapy for depression.Nature medicine · 2022Trial
- Executive Functioning Is Linked to Internalizing Symptoms in Autistic Adults With Higher Support Needs.Autism : the international journal of research and practice · 2026Article
- Dynamic coactivation patterns during repetitive negative thinking: A cross-sectional fMRI study.Psychological medicine · 2026Article
- Exercise intervention for rumination: from neural mechanisms to clinical applications.Frontiers in psychology · 2026Review
- Article
- Lysergic acid diethylamide-derived excitatory/inhibitory ratio change enhances global synchrony in functional brain dynamics.PLoS computational biology · 2025Article
- An integrative model of perseverative thinking.Dialogues in clinical neuroscience · 2025Review
- The Desegregation of Neural Networks During Worry Induction in Late Life: An Effective Connectivity Analysis.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Article
- Resting-State and Task-Based Functional Connectivity Reveal Distinct mPFC and Hippocampal Network Alterations in Major Depressive Disorder.Brain sciences · 2025Article
- Increased insular functional connectivity during repetitive negative thinking in major depression and healthy volunteers.Psychological medicine · 2025Article
- Neural correlates of rumination in remitted depressive episodes: Brain network connectivity and topology analyses.World journal of psychiatry · 2025Article
- Worry and rumination elicit similar neural representations: neuroimaging evidence for repetitive negative thinking.Cognitive, affective & behavioral neuroscience · 2025Article
- A randomized controlled trial of computerized cognitive training to improve working memory in individuals with elevated repetitive negative thinking: Behavioral and neural outcomes.Journal of mood and anxiety disorders · 2025Article
- Dynamic functional connectivity signatures of focused attention on the breath in adolescents.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Resting-state functional connectivity between the frontoparietal network and the default mode network is aberrantly increased in ankylosing spondylitis.BMC musculoskeletal disorders · 2025Article
- An investigation of the interaction of trait repetitive negative thinking and neuroticism on brain activity during negative self-referential processing: a cross-sectional fMRI study.Social cognitive and affective neuroscience · 2025Article
- Modulation of functional network co-activation pattern dynamics following ketamine treatment in major depression.Imaging neuroscience (Cambridge, Mass.) · 2025Article
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6 authors.
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Abstract
Repetitive negative thinking (RNT) is a maladaptive response to sadness and a transdiagnostic risk-factor. A critical challenge hampering attempts to promote more adaptive responses to sadness is that the between-person characteristics associated with the tendency for RNT remain uncharacterized. From the perspective of the impaired disengagement hypothesis, we examine between-person differences in blood-oxygen-level-dependent (BOLD) functional networks underlying cognitive conflict signaling, self-referential thought, and cognitive flexibility, and the association between sadness and RNT in daily life. We pair functional magnetic resonance imaging with ambulatory assessments deployed 10 times per day over 4 consecutive days measuring momentary sadness and RNT from 58 participants (40 female, mean age = 36.69 years; 29 remitted from a lifetime episode of Major Depression) in a multilevel model. We show that RNT increases following sadness for participants with higher than average between-network connectivity of the default mode network and the fronto-parietal network. We also show that RNT increases following increases in sadness for participants with lower than average between-network connectivity of the fronto-parietal network and the salience network. We also find that flexibility of the salience network's pattern of connections with brain regions is protective against increases in RNT following sadness. Our findings highlight the importance of functional brain networks implicated in cognitive conflict signaling, self-referential thought, and cognitive flexibility for understanding maladaptive responses to sadness in daily life and provide support for the impaired disengagement hypothesis of RNT.
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