Evidence map›Paper›PMID 31534060›Full record

ArticleThe Journal of veterinary medical science2019

Transcriptional responses of LSm14A after infection of blue eggshell layers with Newcastle disease viruses.

Lang Tian, Changhua Wu, Guilan Wen, Changhong Li

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of veterinary medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Cytosolic Sensors for Pathogenic Viral and Bacterial Nucleic Acids in Fish.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Lang TianCollege of Animal Sciences, Preventive Veterinary Laboratory, Guizhou University, Guiyang 550025 China.
Changhua WuAgricultural and Rural Bureau of Anshun City, Guizhou Province, Anshun 561000 China.
Guilan WenCollege of Animal Sciences, Preventive Veterinary Laboratory, Guizhou University, Guiyang 550025 China.
Changhong LiCollege of Animal Sciences, Preventive Veterinary Laboratory, Guizhou University, Guiyang 550025 China.
Guizhou University · CNAnshun University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

LSm14A is a key innate immunity component of processing body (P-body) that mediates interferon-β (IFN-β) signaling by viral RNA. This is the first study to report chicken LSm14A (cLSm14A) cloning from blue eggshell layer, high tibia and frizzle chickens. The cLSm14A gene, encoding 461 amino acids, is highly homologous in the three types of chickens. The cLSm14A was extensively expressed in several tissues. The transcriptional level of cLSm14A was significantly increased in various stages of Newcastle disease virus (NDV) infection. In HEK293 cells, full length cLSm14A from blue eggshell layer was localized in the cytoplasm as dots. The results of this study indicated that cLSm14A is an important sensor that mediates innate immunity in chicken against NDV infections.

Indexed as

ChickensNewcastle disease virusAnimalsAvian ProteinsCloning, MolecularHEK293 CellsHumansImmunity, InnateNewcastle DiseaseOrgan SpecificityTranscription, GeneticAvian Proteinsblue eggshell layerInnate immunityLSm14ANewcastle disease viruses

Identifiers

PMID31534060
PMCPMC6863722
OpenAlexW2974539255

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.