Evidence map›Paper›PMID 31534035›Full record

ArticleJournal of virology2019

Diversity of Dromedary Camel Coronavirus HKU23 in African Camels Revealed Multiple Recombination Events among Closely Related Betacoronaviruses of the Subgenus Embecovirus.

Ray T Y So, Daniel K W Chu, Eve Miguel, Ranawaka A P M Perera, Jamiu O Oladipo, Ouafaa Fassi-Fihri, Gelagay Aylet, Ronald L W Ko, Ziqi Zhou, Mo-Sheung Cheng and 7 more

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 37 citations in OpenAlex.

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  14. A 21L/BA.2-21K/BA.1 "MixOmicron" SARS-CoV-2 hybrid undetected by qPCR that screen for variant in routine diagnosis.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 8 countries.

Ray T Y SoSchool of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, Republic of China.
Daniel K W ChuSchool of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, Republic of China.
Eve MiguelMIVEGEC Maladies Infectieuses et Vecteurs: Ecologie, Génétique, Evolution et Contrôle, IRD L'Institut de Recherche pour le Développement, CNRS Centre National de Recherche Scientifique, Universitè de Montpellier, Montpellier, France.
Ranawaka A P M PereraSchool of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, Republic of China.
Jamiu O OladipoSchool of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, Republic of China.
Ouafaa Fassi-FihriInstitut Agronomique et Vétérinaire, Hassan II Université, Rabat, Morocco.
Gelagay AyletPan African Veterinary Center of the African Union (AU-PANVAC), Debre Zeit, Ethiopia.
Ronald L W KoSchool of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, Republic of China.
Ziqi ZhouSchool of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, Republic of China.
Mo-Sheung ChengSchool of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, Republic of China.
Sulyman A KurangaDepartment of Surgery, Faculty of Clinical Sciences, University of Ilorin, Ilorin, Nigeria.
François L RogerAnimal, Santé, Territoires, Risques et Ecosystèmes, Centre de Coopération Internationale en Recherche Agronomique pour le Développement, Institut National de la Recherche Agronomique, Université de Montpellier, Montpellier, France.
Veronique ChevalierAnimal, Santé, Territoires, Risques et Ecosystèmes, Centre de Coopération Internationale en Recherche Agronomique pour le Développement, Institut National de la Recherche Agronomique, Université de Montpellier, Montpellier, France.
Richard J WebbySt. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Patrick C Y WooDepartment of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, Republic of China.ORCID 0000-0001-9401-1832
Leo L M PoonSchool of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, Republic of China.
Malik PeirisSchool of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, Republic of China malik@hku.hk.ORCID 0000-0001-8217-5995
University of Hong Kong · HKCentre de Coopération Internationale en Recherche Agronomique pour le Développement · FRUniversity of Ilorin · NGAfrican Union · ETCentre National de la Recherche Scientifique · FRInstitut Agronomique et Vétérinaire Hassan II · MASt. Jude Children's Research Hospital · US

Funding

NIAID NIH HHS HHSN272201400006C
6 · The paper itself

Abstract

Genetic recombination has frequently been observed in coronaviruses. Here, we sequenced multiple complete genomes of dromedary camel coronavirus HKU23 (DcCoV-HKU23) from Nigeria, Morocco, and Ethiopia and identified several genomic positions indicative of cross-species virus recombination events among other betacoronaviruses of the subgenus Embecovirus (clade A beta-CoVs). Recombinant fragments of a rabbit coronavirus (RbCoV-HKU14) were identified at the hemagglutinin esterase gene position. Homolog fragments of a rodent CoV were also observed at 8.9-kDa open reading frame 4a at the 3' end of the spike gene. The patterns of recombination differed geographically across the African region, highlighting a mosaic structure of DcCoV-HKU23 genomes circulating in dromedaries. Our results highlighted active recombination of coronaviruses circulating in dromedaries and are also relevant to the emergence and evolution of other betacoronaviruses, including Middle East respiratory syndrome coronavirus (MERS-CoV).

Indexed as

Genetic VariationRecombination, GeneticAnimalsAntibodies, NeutralizingBetacoronavirusCamelusCoronavirusCoronavirus InfectionsEthiopiaEvolution, MolecularGenome, ViralGenotypeMiddle East Respiratory Syndrome CoronavirusMoroccoNigeriaOpen Reading FramesAntibodies, Neutralizingbetacoronavirusescoronavirusesdromedary camelsevolutionphylogenyrecombination

Identifiers

PMID31534035
PMCPMC6854494
OpenAlexW2974693537

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.