Evidence map›Paper›PMID 31534034›Full record

ArticleJournal of virology2019

Identification of the First Gene Transfer Agent (GTA) Small Terminase in

D Sherlock, J X Leong, P C M Fogg

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Loss of the Rhodobacter capsulatus Serine Acetyl Transferase Gene,Applied and environmental microbiology · 2022
    Article
  7. Riboflavin synthesis from gaseous nitrogen and carbon dioxide by a hybrid inorganic-biological system.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Gene Transfer Agents in Symbiotic Microbes.Results and problems in cell differentiation · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

D SherlockBiology Department, University of York, York, United Kingdom.
J X LeongBiology Department, University of York, York, United Kingdom.
P C M FoggBiology Department, University of York, York, United Kingdom paul.fogg@york.ac.uk.ORCID 0000-0001-5324-4293
University of York · GB

Funding

Wellcome TrustWellcome Trust 109363/Z/15/Z
6 · The paper itself

Abstract

Genetic exchange mediated by viruses of bacteria (bacteriophages) is the primary driver of rapid bacterial evolution. The priority of viruses is usually to propagate themselves. Most bacteriophages use the small terminase protein to identify their own genome and direct its inclusion into phage capsids. Gene transfer agents (GTAs) are descended from bacteriophages, but they instead package fragments of the entire bacterial genome without preference for their own genes. GTAs do not selectively target specific DNA, and no GTA small terminases are known. Here, we identified the small terminase from the model

Indexed as

DNA PackagingGene Transfer, HorizontalBacteriophagesCapsid ProteinsDNADNA-Binding ProteinsDrug Resistance, BacterialEndodeoxyribonucleasesEvolution, MolecularMultigene FamilyRhodobacter capsulatusSequence AlignmentSequence Analysis, ProteinTransduction, GeneticVirus AssemblyCapsid ProteinsDNADNA-Binding ProteinsEndodeoxyribonucleasesterminaseantibiotic resistanceantimicrobial resistancebacterial evolutionbacteriophagebacteriophage assemblyDNA-binding proteinsDNA packaginggene transfergene transfer agenthorizontal gene transferRhodobacterterminasetransductionvirus

Identifiers

PMID31534034
PMCPMC6854486
OpenAlexW2974364486

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.