Evidence map›Paper›PMID 31533997›Full record

ArticlemSphere2019

Recovirus NS1-2 Has Viroporin Activity That Induces Aberrant Cellular Calcium Signaling To Facilitate Virus Replication.

Alicia C Strtak, Jacob L Perry, Mark N Sharp, Alexandra L Chang-Graham, Tibor Farkas, Joseph M Hyser

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
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  9. Article
  10. Host IPmBio · 2024
    Article
  11. Breaking the Ice: A Review of Phages in Polar Ecosystems.Methods in molecular biology (Clifton, N.J.) · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Conflicts over calcium and the treatment of COVID-19.Evolution, medicine, and public health · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Alicia C StrtakAlkek Center for Metagenomic and Microbiome Research, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Jacob L PerryAlkek Center for Metagenomic and Microbiome Research, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Mark N SharpAlkek Center for Metagenomic and Microbiome Research, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Alexandra L Chang-GrahamAlkek Center for Metagenomic and Microbiome Research, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Tibor FarkasDepartment of Pathobiological Sciences, Louisiana State University School of Veterinary Medicine, Baton Rouge, Louisiana, USA.
Joseph M HyserAlkek Center for Metagenomic and Microbiome Research, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA Joseph.Hyser@bcm.edu.
Baylor College of Medicine · USLouisiana State University · US

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI Michael M Ittmann · 2007 to 2026
$73.9M
X-ray Crystallographic Studies on CalicivirusesP01AI057788 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI PRASAD, BIDADI VENKATARAM · 2004 to 2024
$34.4M
Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI James Versalovic · 2001 to 2026
$28.3M
TRAINING PROGRAM IN CELL AND MOLECULAR BIOLOGYT32GM008231 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI NELSON, DAVID LOREN · 1990 to 2019
$7.2M
Training Supplement in Enteric Virus Exploitation of Calcium SignalingR01DK115507 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Joseph M. Hyser · 2018 to 2026
$5.0M
Enteric Calicivirus Viroporin-Mediated Calcium SignalingR21AI137710 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI FARKAS, TIBOR, HYSER, JOSEPH M. · 2019 to 2020
$441k
Regulation of secretory diarrhea by ER-PM junction signalingF30DK112563 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI CHANG-GRAHAM, ALEXANDRA · 2017 to 2019
$128k
NCI NIH HHS P30 CA125123NIAID NIH HHS P01 AI057788NIAID NIH HHS R21 AI137710NIDDK NIH HHS F30 DK112563NIDDK NIH HHS P30 DK056338NIDDK NIH HHS R01 DK115507NIGMS NIH HHS T32 GM008231
6 · The paper itself

Abstract

Enteric viruses in the

Indexed as

Calcium SignalingVirus ReplicationAnimalsCalciumCaliciviridaeCell LineHomeostasisHost Microbial InteractionsIon ChannelsMacaca mulattaViral Nonstructural ProteinsCalciumIon ChannelsViral Nonstructural ProteinscalciumcalicivirusGCaMPviroporin

Identifiers

PMID31533997
PMCPMC6751491
OpenAlexW2974793240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.