Evidence map›Paper›PMID 31533965›Full record

ArticleGut2020

Quantitative fluorescence endoscopy: an innovative endoscopy approach to evaluate neoadjuvant treatment response in locally advanced rectal cancer.

Jolien J J Tjalma, Marjory Koller, Matthijs D Linssen, Elmire Hartmans, Steven J de Jongh, Annelies Jorritsma-Smit, Arend Karrenbeld, Elisabeth G de Vries, Jan H Kleibeuker, Jan Pieter Pennings and 8 more

Registry-linked trialAbstract read
In one paragraph

Article in Gut, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04112212 (Using Fluorescently Labeled Vedolizumab to Visualize Local Drug Distribution During Colonoscopy and Identify Mucosal Target Cells in Patients With Inflammatory Bowel Disease), which is not on this map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04112212 phase1completednot on this map

Using Fluorescently Labeled Vedolizumab to Visualize Local Drug Distribution During Colonoscopy and Identify Mucosal Target Cells in Patients With Inflammatory Bowel Disease

TypeinterventionalSponsorUniversity Medical Center GroningenRan2020 to 2023Enrolled38ConditionsCrohn Disease, Colitis, UlcerativeArmsFluorescence molecular imaging procedure using vedolizumab-800CW, Fluorescence molecular imaging procedure without prior administration of vedolizumab-800CW, Fluorescence molecular imaging procedure using vedolizumab-800CW with prior administration of unlabeled vedolizumab
3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Targeted Fluorescence Imaging of Bevacizumab-800CW in Patients with Neovascular Age-Related Macular Degeneration.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Jolien J J Tjalma *Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.ORCID 0000-0003-2412-0691
Marjory Koller *Department of Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Matthijs D LinssenDepartment of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Elmire HartmansDepartment of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Steven J de JonghDepartment of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Annelies Jorritsma-SmitDepartment of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Arend KarrenbeldDepartment of Pathology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Elisabeth G de VriesDepartment of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Jan H KleibeukerDepartment of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Jan Pieter PenningsDepartment of Radiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Klaas HavengaDepartment of Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Patrick Hjh HemmerDepartment of Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Geke Ap HospersDepartment of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Boudewijn van EttenDepartment of Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Vasilis NtziachristosInstitute for Biological and Medical Imaging, Helmholtz Zentrum München, Munich, Germany.
Gooitzen M van DamDepartment of Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Dominic J RobinsonOtolaryngology and Head and Neck Surgery, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Wouter B NagengastDepartment of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands w.b.nagengast@umcg.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Area Under CurveChemoradiotherapy, AdjuvantEndoscopy, GastrointestinalFibrosisFluorescenceHumansMagnetic Resonance ImagingNeoadjuvant TherapyNeoplasm, ResidualPilot ProjectsPredictive Value of TestsRectal NeoplasmsRectumROC CurveTreatment OutcomeVascular Endothelial Growth Factor AVascular Endothelial Growth Factor AVEGFA protein, humancolorectal cancercolorectal surgeryfluorescence endoscopyimagingmolecular oncology

Identifiers

PMID31533965
PMCPMC7034345

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.