Evidence map›Paper›PMID 31533864›Full record

ArticleJournal of biomedical semantics2019

Ontology based mining of pathogen-disease associations from literature.

Şenay Kafkas, Robert Hoehndorf

Abstract read
In one paragraph

Article in Journal of biomedical semantics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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  10. Ontology based text mining of gene-phenotype associations: application to candidate gene prediction.Database : the journal of biological databases and curation · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Şenay KafkasComputational Bioscience Research Center, King Abdullah University of Science and Technology, Thuwal, 23955-6900, Saudi Arabia. senay.kafkas@kaust.edu.sa.ORCID 0000-0001-7509-5786
Robert HoehndorfComputational Bioscience Research Center, King Abdullah University of Science and Technology, Thuwal, 23955-6900, Saudi Arabia.ORCID 0000-0001-8149-5890

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfectious diseases claim millions of lives especially in the developing countries each year. Identification of causative pathogens accurately and rapidly plays a key role in the success of treatment. To support infectious disease research and mechanisms of infection, there is a need for an open resource on pathogen-disease associations that can be utilized in computational studies. A large number of pathogen-disease associations is available from the literature in unstructured form and we need automated methods to extract the data.

resultsWe developed a text mining system designed for extracting pathogen-disease relations from literature. Our approach utilizes background knowledge from an ontology and statistical methods for extracting associations between pathogens and diseases. In total, we extracted a total of 3420 pathogen-disease associations from literature. We integrated our literature-derived associations into a database which links pathogens to their phenotypes for supporting infectious disease research.

conclusionsTo the best of our knowledge, we present the first study focusing on extracting pathogen-disease associations from publications. We believe the text mined data can be utilized as a valuable resource for infectious disease research. All the data is publicly available from https://github.com/bio-ontology-research-group/padimi and through a public SPARQL endpoint from http://patho.phenomebrowser.net/ .

Indexed as

Biological OntologiesCommunicable DiseasesData MiningInternetInfectious diseasePathogenPathogen–disease associationRelationship extractionText mining

Identifiers

PMID31533864
PMCPMC6751637

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.