Evidence map›Paper›PMID 31533759›Full record

Observational studyJournal of cardiothoracic surgery2019

Left ventricular dysfunction postsurgical patent ductus arteriosus ligation in children: predictor factors analysis.

Mohamed Abdel-Bary, Khaled Abdalla Abdel-Baseer, Ahmed Fathy Abdel-Latif, Mohamed Abdella Abdel-Naser, Mahmoud Nafie, Karam Mosallam Eisa

Registry-linked trialOpen access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of cardiothoracic surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04018079 (Left Ventricular Dysfunction Post Surgical Patent Ductus Arteriosus Ligation in Children), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04018079 completednot on this map

Left Ventricular Dysfunction Post Surgical Patent Ductus Arteriosus Ligation in Children: Predictor Factors Analysis

Typeobservational_patient_registrySponsorSouth Valley UniversityRan2015 to 2018Enrolled50ConditionsCongenital Heart Disease in Children
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mohamed Abdel-BaryDepartment of cardiothoracic surgery, Qena Faculty of Medicine, South Valley University, Safaga Road, Qena, 83523, Egypt. Dr_abdelbary@med.svu.edu.eg.ORCID http://orcid.org/0000-0002-7734-9089
Khaled Abdalla Abdel-BaseerDepartment of Pediatrics, Qena Faculty of Medicine, South Valley University, Qena, Egypt.ORCID http://orcid.org/0000-0002-5761-0614
Ahmed Fathy Abdel-LatifDepartment of Anaesthesia and ICU, Qena Faculty of Medicine, South Valley University, Qena, Egypt.ORCID http://orcid.org/0000-0002-3434-9361
Mohamed Abdella Abdel-NaserDepartment of Anaesthesia and ICU, Faculty of Medicine, Assiut University, Asyut, Egypt.ORCID http://orcid.org/0000-0002-3798-2322
Mahmoud NafieNational heart institute, Cairo, Egypt.ORCID http://orcid.org/0000-0003-4400-8154
Karam Mosallam EisaDepartment of cardiothoracic surgery, Qena Faculty of Medicine, South Valley University, Safaga Road, Qena, 83523, Egypt.
South Valley University · EGAssiut University · EGNational Heart Institute · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify the predictor factors of left ventricular (LV) dysfunction following patent ductus arteriosus (PDA) surgical ligation.

backgroundPDA is viewed as a noticeable amongst the most widely recognized congenital heart defects in children and its closure is responsible for many hemodynamic changes that require intervention and care.

methodsA retrospective study included fifty children with isolated PDA treated by surgical ligation from June 2015 to June 2018. The LV dimensions and systolic function were assessed by two-dimensional echocardiography pre and post PDA ligation. All cases were followed-up on the first-day, 1 month and 6 months post ligation.

resultsThe mean age of cases was 15.78 ± 7.58 months and 72% were females. The mean duct size was 4.08 ± 1.25 mm. There was a marked decrease in LVEDd, LA/Ao, EF and FS in the first-day post ligation contrasted with pre ligation values. Moreover, an amazing decline in LVEDd and LA/Ao ratio was observed 1 month post ligation contrasted with the early post ligation status with asynchronous improvement of FS and EF at one and 6 months postoperatively.

conclusionPDA ligation is associated with a noteworthy LV systolic dysfunction within the first day post ligation; that in a significant number of patients may require anti-failure measures, prolong the hospital stay and necessitate a regular follow up and monitoring of LV function. PDA size, age, preoperative LVEDd and FS can be considered as predictor factors for suspicion of acute decrease in the LV systolic function early post PDA ligation.

trial registrationClinTrial.Gov NCT04018079 .

Indexed as

Cardiac Surgical ProceduresChild, PreschoolDuctus Arteriosus, PatentEchocardiographyFemaleHemodynamicsHumansInfantMalePredictive Value of TestsRetrospective StudiesRisk AssessmentSystoleVentricular Dysfunction, LeftVentricular Function, LeftCongenital heart diseaseLA/Ao ratioLV systolic function and dimensionsPDA ligation

Identifiers

PMID31533759
PMCPMC6751680
OpenAlexW2974192202

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.