ArticleBMC public health2019
Contact screening and risk factors for TB among the household contact of children with active TB: a way to find source case and new TB cases.
Article in BMC public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Risk factors for the development of tuberculosis among the pediatric population: a systematic review and meta-analysis.European journal of pediatrics · 2023Pooled it
- Key risk factors for pulmonary vs. extrapulmonary tuberculosis: a comparative study in Southwest Ethiopia.Journal of clinical tuberculosis and other mycobacterial diseases · 2026Article
- BCG vaccination and household TB exposure in childhood tuberculosis: a community-based case-control study in rural Bangladesh.BMC infectious diseases · 2026Article
- A clinical scoring system to predict tuberculous lymphadenitis in settings with high disease burden.Scientific reports · 2025Article
- Predictors of pediatric tuberculosis disease in a pastoralist community, Turkana County, Kenya: a case-control study.BMC infectious diseases · 2025Article
- Clinical characteristics and prognostic outcomes of pediatric tuberculosis in a tertiary care center in China: a 10-year retrospective cohort.IJID regions · 2025Article
- Article
- Risk Factors of Childhood Tuberculosis in the Centre Region of Cameroon: An Unmatched Case-Control Study.Interdisciplinary perspectives on infectious diseases · 2025Article
- Article
- Tuberculosis screening among cough suppressant buyers in pharmacies and drug outlets in Guinea: a cross-sectional study.BMJ open respiratory research · 2024Article
- Article
- Incidence and risk factors of tuberculosis among 420 854 household contacts of patients with tuberculosis in the 100 Million Brazilian Cohort (2004-18): a cohort study.The Lancet. Infectious diseases · 2024Article
- Timeliness metrics for screening and preventing TB in household contacts of pulmonary TB patients in Kenya.IJTLD open · 2024Article
- Development and validation of a risk prediction model for pulmonary tuberculosis among presumptive tuberculosis cases in Ethiopia.BMJ open · 2023Article
- Tuberculosis infection among children under six in contact with smear positive cases: A study in a hyper endemic area of Iran.Journal of clinical tuberculosis and other mycobacterial diseases · 2023Article
- The Contribution of Chest Radiography to the Clinical Management of Children Exposed to Tuberculosis.American journal of respiratory and critical care medicine · 2022Article
- Changing patterns of household transmission of tuberculosis in an eastern state of India: The impact of COVID19 pandemic.The Indian journal of tuberculosis · 2022Article
- Tuberculosis challenges: Resistance, co-infection, diagnosis, and treatment.European journal of microbiology & immunology · 2022Review
- Drug resistance patterns, treatment outcomes and factors affecting unfavourable treatment outcomes among extensively drug resistant tuberculosis patients in Pakistan; a multicentre record review.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2022Article
- Sputum smears quality inspection using an ensemble feature extraction approach.Frontiers in public health · 2022Article
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSource case investigation, for children with tuberculosis (TB), is conducted to establish the source of infection and to minimize the extent of on-going transmission from infectious persons in the community. The aim of the study was to evaluate the secondary TB cases and to investigate the risk factors in developing TB among the household contacts (HHC) of children with active TB.
methodsA prospective cross-sectional study was conducted where 443 caregivers, of 508 children with active TB receiving treatment, were interviewed using a structured questionnaire. Logistic regression analysis was used to examine the risk factors for TB.
resultsA total of 2397 family members at the median of 5 persons were recorded. Of these, 223 (9.3%) were screened on symptoms basis and 35 (15.7%) of these contacts were diagnosed with TB. Multivariate analysis revealed HHC with TB (OR = 15.288, 95% CI: 5.378-43.457), HHC with smoking (OR = 7.094, 95% CI: 2.128-23.648), and contact of > 18 h with TB individual (OR = 4.681, 95% CI: 1.198-18.294) as statistically significant risk factors of TB among the HHC.
conclusionWith the current system of contact screening for TB, only 9.3% of all HHC were screened. The low rates of contacts screened are possibly a repercussion of the passive nature of the program, which mainly depend on distinctive clinical symptoms being experienced by the contacts. Strategies are required to certify adherence with contact screening among children with active TB and to critically consider the factors responsible for TB transmission.
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