ArticleBMC geriatrics2019
Impact of training and structured medication review on medication appropriateness and patient-related outcomes in nursing homes: results from the interventional study InTherAKT.
Article in BMC geriatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Pooled it
- Implementation of interprofessional quality circles on deprescribing in Swiss nursing homes: an observational study.BMC geriatrics · 2023Pooled it
- Quality standards for safe medication in nursing homes: development through a multistep approach including a Delphi consensus study.BMJ open · 2021Guideline
- [Medication supply and polypharmacy in long-term care : An overview of possible interventions and the question of a functioning concept].Zeitschrift fur Gerontologie und Geriatrie · 2025Review
- Knowledge, counseling practices, and educational gaps related to drug-food interactions among healthcare professionals in Saudi Arabia: a cross-sectional study.Frontiers in medicine · 2025Article
- Structured medication reviews for adults with multimorbidity and polypharmacy in primary care: a systematic review protocol.BMJ open · 2024Article
- Evaluation of the Effect of a Safe Medication Strategy on Potentially Inappropriate Medications, Polypharmacy and Anticholinergic Burden for People with Dementia: An Intervention Study.Healthcare (Basel, Switzerland) · 2023Article
- Nursing Home-Sensitive Hospitalizations and the Relevance of Telemedicine: A Scoping Review.International journal of environmental research and public health · 2022Article
- Determine the impact of a structured pharmacist-led medication review - a controlled intervention study to optimise medication safety for residents in long-term care facilities.BMC geriatrics · 2022Article
- Suicidal and accidental drug poisoning mortality among older adults and working-age individuals in Spain between 2000 and 2018.BMC geriatrics · 2022Article
- Healthcare Professionals' Views on the Management of Medication Complexities in the Elderly With Mental Health Disorders: A Cross-Sectional Study.Frontiers in psychiatry · 2022Article
- Expert-based medication reviews to reduce polypharmacy in older patients in primary care: a northern-Italian cluster-randomised controlled trial.BMC geriatrics · 2021Review
- Ethical Tenets of PRN Medicines Management in Healthcare Settings: A Clinical Perspective.Pharmacy (Basel, Switzerland) · 2021Article
- Epidemiology and associated factors of polypharmacy in older patients in primary care: a northern Italian cross-sectional study.BMC geriatrics · 2021Article
- Are medications safely used by residents in elderly care homes? - A multi-centre observational study from Sri Lanka.PloS one · 2020Observational
- The Prevalence of Selected Potential Drug-Drug Interactions of Analgesic Drugs and Possible Methods of Preventing Them: Lessons Learned From the Analysis of the Real-World National Database of 38 Million Citizens of Poland.Frontiers in pharmacology · 2020Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUncoordinated interprofessional communication in nursing homes increases the risk of polypharmacy and inappropriate medication use. This may lead to augmented frequency of adverse drug events, hospitalizations and mortality. The aims of this study were (1) to improve interprofessional communication and medication safety using a combined intervention and thus, (2) to improve medication appropriateness and health-related outcomes of the included residents.
methodsThe single-arm interventional study (2014-2017) was conducted in Muenster, Germany and involved healthcare professionals and residents of nursing homes. The intervention consisted of systematic education of participating healthcare professionals and of a structured interprofessional medication review which was performed via an online communication platform. The primary endpoint was assessed using the Medication Appropriateness Index MAI. Secondary endpoints were: cognitive performance, delirium, agitation, mobility, number of drugs, number of severe drug-drug interactions and appropriateness of analgesics. Outcomes were measured before, during and after the intervention. Data were analyzed using descriptive and inference-statistical methods.
resultsFourteen general practitioners, 11 pharmacists, 9 nursing homes and 120 residents (n = 83 at all testing times) participated. Overall MAI sum-score decreased significantly over time (mean reduction: -7.1, CI
conclusionMedication appropriateness increased particularly in residents with high baseline MAI sum-scores. Cognitive decline of participating residents was seemingly decelerated when compared with epidemiologic studies. A controlled trial is required to confirm these effects. Interprofessional interaction was structured and performance of medication reviews was facilitated as the online communication platform provided unlimited and consistent access to all relevant and updated information.
trial registrationDRKS Data Management, ID: DRKS00007900 , date of registration: 2015-09-02 (retrospectively registered i.e. 6 weeks after commencement of the first data collection).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.