ArticleTechnology in cancer research & treatment2019
Time-Dependent Impact of Irreversible Electroporation on Pathology and Ablation Size in the Porcine Liver: A 24-Hour Experimental Study.
Article in Technology in cancer research & treatment, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 22 citations in OpenAlex.
- In Situ Vaccination by Tumor Ablation: Principles and Prospects for Systemic Antitumor Immunity.Vaccines · 2025Review
- Reproducible spectral CT thermometry with liver-mimicking phantoms for image-guided thermal ablation.Physics in medicine and biology · 2024Article
- Irreversible electroporation promotes a pro-inflammatory tumor microenvironment and anti-tumor immunity in a mouse pancreatic cancer model.Frontiers in immunology · 2024Article
- Assessment of efficacy and safety of advanced endoscopic irreversible electroporation catheter in the esophagus.Scientific reports · 2023Article
- Complications Risk Assessment and Imaging Findings of Thermal Ablation Treatment in Liver Cancers: What the Radiologist Should Expect.Journal of clinical medicine · 2022Review
- Complications after Thermal Ablation of Hepatocellular Carcinoma and Liver Metastases: Imaging Findings.Diagnostics (Basel, Switzerland) · 2022Review
- Liver tissue remodeling following ablation with irreversible electroporation in a porcine model.Frontiers in veterinary science · 2022Article
- Combinatorial effect of radium-223 and irreversible electroporation on prostate cancer bone metastasis in mice.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2021Article
- Recent progress in pulsed electric field ablation for liver cancer.World journal of gastroenterology · 2020Review
- Dynamics of Cell Death After Conventional IRE and H-FIRE Treatments.Annals of biomedical engineering · 2020Article
- Intraprocedural Transcatheter Intraarterial Perfusion (TRIP)-MRI for Evaluation of Irreversible Electroporation Therapy Response in a Rabbit Liver Tumor Model.Clinical and experimental gastroenterology · 2020Article
- Starting a Fire Without Flame: The Induction of Cell Death and Inflammation in Electroporation-Based Tumor Ablation Strategies.Frontiers in oncology · 2020Review
- Assessment of Hepatic Lesions After non-Thermal Tumor Ablation by Irreversible Electroporation in a Pig Model.Technology in cancer research & treatmentArticle
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Irreversible electroporation causes cell death through low frequency, high voltage electrical pulses and is increasingly used to treat non-resectable cancers. A recent systematic review revealed that tissue damage through irreversible electroporation is time-dependent, but the impact of time on the ablation zone size remains unknown. Irreversible electroporation ablations were performed hourly during 24 consecutive hours in the peripheral liver of 2 anaesthetized domestic pigs using clinical treatment settings. Immediately after the 24th ablation, the livers were harvested and examined for tissue response in time based on macroscopic and microscopic pathology. The impact of time on these outcomes was assessed with Spearman rank correlation test. Ablation zones were sharply demarcated as early as 1 hour after treatment. During 24 hours, the ablation zones showed a significant increase in diameter (rs = 0.493,
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Registered trials
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