Evidence map›Paper›PMID 31533351›Full record

ArticleInternational journal of molecular sciences2019

Mouse Tryptase Gene Expression is Coordinately Regulated by GATA1 and GATA2 in Bone Marrow-Derived Mast Cells.

Kinuko Ohneda, Shin'ya Ohmori, Masayuki Yamamoto

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. TheiScience · 2022
    Article
  8. Article
  9. iScience · 2021
    Article
  10. Anaphylaxis: Focus on Transcription Factor Activity.International journal of molecular sciences · 2021
    Review
  11. Review
  12. Review
  13. Article
  14. Phenotypic and Functional Diversity of Mast Cells.International journal of molecular sciences · 2020
    Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kinuko OhnedaDepartment of Pharmacy, Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki 370-0033, Japan. kohneda@megabank.tohoku.ac.jp.
Shin'ya OhmoriDepartment of Pharmacy, Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki 370-0033, Japan.
Masayuki YamamotoDepartment of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai 980-8573, Japan.
Takasaki University of Health and Welfare · JPTohoku University · JP

Funding

Japan Society for the Promotion of Science 18K06920, 17K08643
6 · The paper itself

Abstract

Mast cell tryptases have crucial roles in allergic and inflammatory diseases. The mouse tryptase genes represent a cluster of loci on chromosome 16p3.3. While their functional studies have been extensively performed, transcriptional regulation of tryptase genes is poorly understood. In this study, we examined the molecular basis of the tryptase gene expression in bone marrow-derived mast cells (BMMCs) of C57BL/6 mice and in MEDMC-BRC6 mast cells. The expression of the

Indexed as

Gene Expression RegulationAnimalsBone Marrow CellsGATA1 Transcription FactorGATA2 Transcription FactorGene Knockout TechniquesGenetic LociMast CellsMicePromoter Regions, GeneticProtein BindingRNA, Small InterferingTryptasesGATA1 Transcription FactorGATA2 Transcription FactorRNA, Small InterferingTryptasesgene transcriptionmast celltryptase

Identifiers

PMID31533351
PMCPMC6770354
OpenAlexW2974923700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.